Publications associées à Photodynamic drug delivery enhancement in tumours does not depend on leukocyte-endothelial interaction in a human mesothelioma xenograft model

Establishment of Reference Intervals of Blood Parameters Among the Healthy Afghan Population

Purpose: This study was designed and conducted to validate the reference values of hematological parameters for healthy adult male and female residents of Kabul city, Afghanistan. Methodology: In this cross-sectional study, the samples were collected accor ...

Dove Medical Press Ltd2024

Neurometabolic profiles of bile duct ligated rats after the treatment with an urease inhibitor – 1H MRS dataset

Cristina Ramona Cudalbu, Dunja Simicic

1H MRS in the cerebellum was used to study the effect of 2-octynohydroxamic acid (2-octynoHA) treatment on the brain of bile duct ligated (BDL) rats (type C hepatic encephalopathy). The study included four groups of rats: negative control group (rats recei ...

Zenodo2023

Spatial Distributions of Diarrheal Cases in Relation to Housing Conditions in Informal Settlements: A Cross-Sectional Study in Abidjan, Côte d’Ivoire

Jérôme Chenal, Vitor Pessoa Colombo, Jürg Utzinger

In addition to individual practices and access to water, sanitation, and hygiene (WASH) facilities, housing conditions may also be associated with the risk of diarrhea. Our study embraced a broad approach to health determinants by looking at housing depriv ...

2023

Associations of genetic and infectious risk factors with coronary heart disease

Roxane De La Harpe, Jacques Fellay, Flavia Aurelia Shoko Hodel, Christian Axel Wandall Thorball, Zhi Ming Xu

Coronary heart disease (CHD) is one of the most pressing health problems of our time and a major cause of preventable death. CHD results from complex interactions between genetic and environmental factors. Using multiplex serological testing for persistent ...

eLIFE SCIENCES PUBL LTD2023

How different charging prices can contribute to the balancing of ride-hailing services with electric vehicles

Nikolaos Geroliminis, Marko Maljkovic, Nils Gustav Nilsson

Motivated by the growing popularity of both the services offered by the ride-hailing companies and the electric vehicles (EVs), we study a scenario in which a central body e.g., the government, wants to influence how the EVs of different ride-hailing compa ...

2022

Geographic clusters of objectively measured physical activity and the characteristics of their built environment in a Swiss urban area

Stéphane Joost, Cédric Gubelmann, Marco André Vieira Ruas, Idris Guessous

Introduction ...

PUBLIC LIBRARY SCIENCE2022

Evaluation of a shortened version of the Action Research Arm Test (ARAT) for upper extremity function after stroke: The Mini-ARAT

Friedhelm Christoph Hummel, Lisa Aïcha Mireille Julie Fleury

Objectives (i) to create a shortened version of the Action Research Arm Test scale, (ii) to investigate its psychometric properties compared to the original scale and (iii) to externally validate it within an independent cohort. Design Prospective longitud ...

SAGE PUBLICATIONS LTD2022

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Stéphane Joost, Idris Guessous

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

ELSEVIER SCI LTD2022

Real-world gait speed estimation, frailty and handgrip strength: a cohort-based study

Kamiar Aminian, Anisoara Ionescu, Abolfazl Soltani

Gait speed is a reliable outcome measure across multiple diagnoses, recognized as the 6th vital sign. The focus of the present study was on assessment of gait speed in long-term real-life settings with the aim to: (1) demonstrate feasibility in large cohor ...

Nature Portfolio2021

Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study

Jean-Yves Meuwly, Mary-Anne Hartley

Background. Lung ultrasonography (LUS) is a promising pragmatic risk-stratification tool in coronavirus disease 2019 (COVID-19). This study describes and compares LUS characteristics between patients with different clinical outcomes. ...

OXFORD UNIV PRESS INC2021

Learning from Failures: Reflections on the Role of Project Design and Design Management in the Procurement of Non-Standard Buildings

Paolo Tombesi

The opening of the Guggenheim Museum in Bilbao in 1997 heralded the beginning of an era in world architecture defined by iconic buildings underpinned by mediatic exposure and the belief in the power of design to leverage urban conditions. Today, a conspicu ...

2021

The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli

Vassily Hatzimanikatis, Georgios Fengos, Tuure Eelis Hameri

Background Significant efforts have been made in building large-scale kinetic models of cellular metabolism in the past two decades. However, most kinetic models published to date, remain focused around central carbon pathways or are built around ad hoc re ...

BMC2021

Is there a difference in how people from different socio-environmental contexts perceive discomfort due to glare from daylight?

Magali Bodart, Jan Wienold, Clotilde Marie A Pierson

Exposure to daylight has much to offer and should be optimised to maximise its potential. In order to harvest its benefits, any visual discomfort from daylight should be anticipated and minimised. Hence, there is the need to predict discomfort from dayligh ...

2022

Stimulation and homogenization of the protoporphyrin IX endogenous production by photobiomodulation to increase the potency of photodynamic therapy

Georges Wagnières, Emmanuel Louis Arthur Gerelli, Jaroslava Joniová, Cyrus Kazemiraad

Protoporphyrin IX (PpIX) is produced in the mitochondria and used as fluorescent contrast agent or photosensitizer after exogenous 5-aminolevulinic acid (ALA) delivery in cancer photodynamic detection and therapy (PDT). Although routinely used in the clini ...

ELSEVIER SCIENCE SA2021

Ultrasonic Doppler flow velocity measurements as a co-indicator for the eco-morphological assessment in a residual flow reach

Giovanni De Cesare, Christian Mörtl, Robin Schroff

It is a complex task to evaluate the effects of a river rehabilitation measure on the riverscape’s habitat mosaic. This study investigated the medium term effects of a rehabilitation measure in a residual flow reach downstream of a hydroelectric dam. The r ...

ETH2021

Low-dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of pleural mesothelioma

Paul Joseph Dyson, Etienne Meylan, Julien Robert Rémi Faget, Maxime Reichenbach, Aspasia Gkasti, Yameng Hao

OBJECTIVES: Malignant pleural mesothelioma (MPM) is a deadly disease with limited treatment options. Approaches to enhance patient immunity against MPM have been tested but shown variable results. Previously, we have demonstrated interesting vascular modul ...

OXFORD UNIV PRESS INC2020

Catechin reduces phototoxic effects induced by protoporphyrin IX-based photodynamic therapy in the chick embryo chorioallantoic membrane

Georges Wagnières, Jaroslava Joniová

Significance: Side effects of many cancer treatments are associated with the production of reactive oxygen species (ROS) in normal tissues. This explains why patients treated by photodynamic therapy (PDT) often suffer from skin photosensitization, whereas ...

SPIE Society of Photo-optical Instrumentation Engineers2020

No difference in 13-year survival after medial pivot or central pivot mobile bearing total knee arthroplasty. A propensity matched comparative analysis

Brigitte Jolles-Haeberli

Purpose The present study was designed to evaluate the long-term results (more than 10 years) of mobile bearing total knee arthroplasty (TKA) and to compare the survival of medial pivot axis (MPA) and central pivot axis (CPA) TKAs. The primary hypothesis w ...

2021

Biology and therapeutic targeting of tumour-associated macrophages

Tim Beltraminelli, Michele De Palma

Macrophages sustain tumour progression by facilitating angiogenesis, promoting immunosuppression, and enhancing cancer cell invasion and metastasis. They also modulate tumour response to anti-cancer therapy in pre-clinical models. This knowledge has motiva ...

WILEY2020

Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis

Medullary thyroid carcinoma (MTC) has been shown to express Prospero homeobox protein 1 (Prox1), a transcription factor whose expression is altered in a variety of human cancers. We conducted a retrospective study on a series of 32 patients with MTC to tes ...

2019