Publications associées à Atom transfer radical additions with the cationic half-sandwich complex [Cp*Ru(PPh3)(2)(CH3CN)]OTf

Oxidative rearrangement of 1,1-disubstituted alkenes to ketones

The Wacker process, which is widely used to convert monosubstituted alkenes into the corresponding methyl ketones, is thought to proceed through a PdII/Pd0 catalytic cycle involving a b-hydride elimination step. This mechanistic scenario is inapplicable to ...

American Association for the Advancement of Science2023

Intermolecular oxidative amination of unactivated alkenes by dual photoredox and copper catalysis

Xile Hu, Xiangli Yi

Oxidative amination of alkenes via amidyl radical addition is potentially an efficient method to generate allylic amines, which are versatile synthetic intermediates to bioactive compounds and organic materials. Here by combining photochemical generation o ...

ROYAL SOC CHEMISTRY2021

New Strategies for the Functionalization of Alkenes Exploiting Tethering Chemistry and Ring Strain

Bastian Antoine Rodolphe Claude Muriel

Amino alcohols, cyclopropanes and nitriles are privileged structural motifs found in the scaffold of natural products and bioactive compounds. In addition, they are versatile building blocks in organic chemistry. The development of new and increasingly eff ...

EPFL2021

Catalytic and antibacterial properties of 3-dentate carboxamide Pd/Pt complexes obtained via a benign route

Kurt Schenk, Farzaneh Fadaei Tirani

The complexes Pd-II(qcq)(OAc) and Pt-II(qcq)Cl have been synthesized using environmentally benign synthesized ligands and characterized by elemental analyses: Fourier transform infrared spectroscopy, UV-visible spectroscopy, H-1 NMR spectroscopy, and X-ray ...

WILEY2020

Synthetic methodologies for C-C and C-N bond formation involving alkyl radicals

Guido Barzanò

C-C and C-N bonds are some of the most common structures in molecules ranging from drugs to catalysts and to food additives. Many coupling reactions were developed to form these types of bonds with excellent selectivity and good performance. Still, the syn ...

EPFL2020

Enantioselective C(sp(3))-C(sp(3)) cross-coupling of non-activated alkyl electrophiles via nickel hydride catalysis

Xile Hu, Runze Mao, Srikrishna Bera

Cross-coupling of two alkyl fragments is an efficient method to produce organic molecules rich in sp(3)-hybridized carbon centres, which are attractive candidate compounds in drug discovery. Enantioselective C(sp(3))-C(sp(3)) coupling is challenging, espec ...

2020

Controlling topology, dynamics and function of polymer brushes via post-polymerization modification

Piotr Mocny

Polymer brushes are a class of thin coatings, where each of chains is tethered to the underlying substrate via one chain end. Densely grafted polymer brushes feature a stretched chain conformation, which in a unique way enhances their lubrication and non-b ...

EPFL2019

Stereoselective synthesis of alkenes via base-metal-catalyzed addition reactions to alkynes and activation of hydrogen peroxide and carbon dioxide by iron complexes

Fedor Zhurkin

Alkene functionality can be found in the majority of natural products, drugs, catalysts and organic materials. Therefore, methods of C-C double bond formation constitute a cornerstone of organic synthesis. Selective formation of either (Z)- or (E)-isomer i ...

EPFL2017

Chemoselective Alkene Hydrosilylation Catalyzed by Nickel Pincer Complexes

Xile Hu, Mickael Montandon-Clerc, Simona Mazza, Ivan Buslov, Jeanne Marine Edith Becouse

Chemoselective hydrosilylation of functionalized alkenes is difficult to achieve using base-metal catalysts. Reported herein is that well-defined bis(amino) amide nickel pincer complexes are efficient catalysts for anti-Markovnikov hydrosilylation of termi ...

Wiley-Blackwell2015

Modulating the Steric, Electronic, and Catalytic Properties of Cp* Ruthenium Half-Sandwich Complexes with β-Diketiminato Ligands

Kay Severin, Rosario Scopelliti, Paul Joseph Dyson, Dominique Schreiber, Katrin Anne Thommes, Andrew Douglas Phillips

Five different types of β-diketiminate ligands, bearing electron-donating to strongly electron-withdrawing substituents, were synthesized and used in the synthesis of Cp* ruthenium complexes (Cp* = η5-C5Me5). One series consists of complexes with a covalen ...

American Chemical Society2011

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem "Ester-Amide/Thiol-Ene" Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

Harm-Anton Klok, Maarten Danial, Matthew Gibson

Herein the concept of tandem postpolymerization modification as a versatile route to synthesize well-defined, highly functionalized polymers is introduced. Poly(pentafluorophenyl methacrylate) obtained by atom transfer radical polymerization was first modi ...

American Chemical Society2011

Ruthenium-Catalyzed Synthesis of 1,5-Dichlorides by Sequential Intermolecular Kharasch Reactions

Kay Severin, Rosario Scopelliti, Aurélien Godinat, Katrin Anne Thommes, Charlotte Buron

Sequential intermolecular atom transfer radical addition reactions of activated dichlorides Cl2CRR′ (R = CN, CO2Et, R′ = H, CN, CO2Et) with two olefins catalyzed by [Cp*RuCl2(PPh3)] in the presence Mg allow the synthesis of linear 1,5-dichlorides. Differen ...

Wiley-Blackwell2011

Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand

Paul Joseph Dyson, Angela Casini, Fabio Edafe

The dinuclear dichloro complexes [(η6-arene)2Ru2(μ-Cl)2Cl2] and [(η5-C5Me5)2M2(μ-Cl)2Cl2] react with 2-(pyridine-2-yl)thiazole (pyTz) to afford the cationic complexes [(η6-arene)Ru(pyTz)Cl]+ (arene = C6H6 (1), p-iPrC6H4Me (2) or C6Me6 (3)) and [(η5-C5Me5)M ...

Elsevier2010

Novel Ruthenium Complexes with Sterically Demanding Cyclopentadienyl Ligands : Syntheses, Reactivity and Catalytic Applications

Barnali Dutta

Investigations of ruthenium halfsandwich complexes have mostly focused on Cp and Cp* based derivatives due to the availability of easily accessible starting materials. However, it is interesting to have complexes with substituted cyclopentadienyl ligands i ...

EPFL2010

Hydrocarboxylation of Terminal Alkenes in Supercritical Carbon Dioxide

Gabor Laurenczy

The catalytic hydrocarboxylation of linear alkenes to carboxylic acids using supercritical carbon dioxide as a solvent was studied. High selectivities in acids have been obtained. The best results were achieved when adding a perfluorinated surfactant to th ...

2008

Water-soluble arene ruthenium complexes containing pyridinethiolato ligands: Synthesis, molecular structure, redox properties and anticancer activity of the cations [(η6-arene)Ru(p-SC5H4NH)3]2+

Paul Joseph Dyson, Anna Katherine Renfrew

The cationic complexes [(η6-arene)Ru(SC5H4NH)3]2+, arene being C6H6 (1), MeC6H5 (2), p-iPrC6H4Me (3) or C6Me6 (4), have been synthesized from the reaction of 4-pyridinethiol with the corresponding precursor (η6-arene)2Ru2(μ2-Cl)2Cl2 and isolated as the chl ...

2008

Dark curing kinetics of UV printing inks by real-time ATR-FTIR spectroscopy

Eric Jacques Nouzille

In UV-curable printing technology, an ink or a varnish is exposed to the UV-light source within a fraction of a second. Subsequent polymerization therefore proceeds in the dark, referred to as dark curing. Because dark curing can be critical and contribute ...

EPFL2007

New polynuclear catalysts for atom-transfer radical addition reactions

Laurent Quebatte

Homo- and heterobimetallic complexes of the late transitions metals have been synthesized by metathesis reactions of the corresponding chloro-bridged dimers. These reactions have the advantage of being fast and giving rise to structurally defined products ...

EPFL2006

Synthesis, Structure and Reactivity of Homo- and Heterobimetallic Complexes of the General Formula [CpRu(m-Cl)3ML] (LM = (arene)Ru, CpRh, Cp*Ir)

Laurent Quebatte, Kay Severin, Rosario Scopelliti

The homo- and heterobimetallic complexes [CpRu(m-Cl)3-ML] [LM = (C6H6)Ru, (cymene)Ru, (1,3,5-C6H3iPr3)Ru, CpRh, CpIr] were prepd. by reaction of [CpRu(m-OMe)]2 with Me3SiCl and subsequent addn. of [LMCl2]2. The complexes [Cp*Ru(m-Cl)3Ru(cymene)] and [C ...

2006

Complexes of a transition metal with 2,2-bipyridine ligands substituted by at least one ammonium alkyl radical, process for their fabrication and their use as redox mediator

Michael Graetzel, Shaik Mohammed Zakeeruddin

Complex of general formula I in which R1, R2 and R3, which may be identical or different, represent separately a linear or branched alkyl radical of 1 to 5 carbon atoms, or, together with the nitrogen atom to which they are attached, a heterocyclic ...

(Asulab S.A., Switz.).1994