Publications associées à COVID-19 epidemic in Switzerland: on the importance of testing, contact tracing and isolation

Challenges of COVID-19 Case Forecasting in the US, 2020-2021

Joseph Chadi Benoit Lemaitre, Pan Xu, Myungjin Kim, Shan Yu, Lei Gao, Weitong Zhang, Wei Cao, Xinyi Li

During the COVID-19 pandemic, forecasting COVID-19 trends to support planning and response was a priority for scientists and decision makers alike. In the United States, COVID-19 forecasting was coordinated by a large group of universities, companies, and ...

Public Library Science2024

Community-Aware Group Testing

Suhas Diggavi, Christina Fragouli, Pavlos Nikolopoulos, Sundara Rajan Srinivasavaradhan

Group testing is a technique that can reduce the number of tests needed to identify infected members in a population, by pooling together multiple diagnostic samples. Despite the variety and importance of prior results, traditional work on group testing ha ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Virtual reality intervention alleviates dyspnoea in patients recovering from COVID-19 pneumonia

Bruno Herbelin, Olaf Blanke, Sylvain Cardin, Oliver Alan Kannape, Jemina Fasola, Aline Schmit, Florian Lance, Sophie Jacqueline Andrée Betka

Background Immersive virtual reality (iVR)-based digital therapeutics are gaining clinical attention in the field of pain management. Based on known analogies between pain and dyspnoea, we investigated the effects of visual respiratory feedback on persiste ...

European Respiratory Soc Journals Ltd2023

Seismic Testing of Adjacent Interacting Masonry Structures

Katrin Beyer, Andrea Penna, Igor Tomic

Masonry buildings form building aggregates around the world in historical centers, which developed as the layout of the city or village densified. In these aggregates, adjacent buildings can share structural walls, connected at the interfaces by interlocki ...

2023

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

Henning Paul-Julius Stahlberg, Didier Trono, Priscilla Turelli, Florence Pojer, Sergey Nazarov, Kelvin Ka Ching Lau, Dongchun Ni, Alexander Myasnikov, Emiko Uchikawa

nvestigation of potential hosts of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is crucial to understanding future risks of spillover and spillback. SARS-CoV-2 has been reported to be transmitted from humans to various animals after req ...

2023

FISHFUZZ: Catch Deeper Bugs by Throwing Larger Nets

Mathias Josef Payer, Jiayuan Zhang, Yuqing Zhang, Flavio Toffalini, Han Zheng

Fuzzers effectively explore programs to discover bugs. Greybox fuzzers mutate seed inputs and observe their execution. Whenever a seed reaches new behavior (e.g., new code or higher execution frequency), it is stored for further mutation. Greybox fuzzers d ...

Usenix Assoc2023

RNA-based nanomedicines and their clinical applications

Yi Wang

RNA-based nanomedicines encompass a range of therapeutic approaches that utilize RNA molecules or molecules that target RNAs for the treatment or prevention of diseases. These include antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), endo ...

Tsinghua Univ Press2023

Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy

Marta Di Fabrizio

All coronaviruses are characterized by spike glycoproteins whose S1 subunits contain the receptor binding domain (RBD). The RBD anchors the virus to the host cellular membrane to regulate the virus transmissibility and infectious process. Although the prot ...

MDPI2023

Specchio-COVID19 cohort study: a longitudinal follow-up of SARS-CoV-2 serosurvey participants in the canton of Geneva, Switzerland

Stéphane Joost, Idris Guessous

Introduction The COVID-19 pandemic has affected billions of people around the world both directly through the infection itself and indirectly through its economic, social and sanitary impact. Collecting data over time is essential for the understanding of ...

BMJ PUBLISHING GROUP2022

Host genomics of SARS-CoV-2 infection

Jacques Fellay, Christian Axel Wandall Thorball

SARS-CoV-2 infected a large fraction of humans in the past 2 years. The clinical presentation of acute infection varies greatly between individuals, ranging from asymptomatic or mild to life-threatening COVID-19 pneumonia with multi-organ complications. De ...

SPRINGERNATURE2022

Identification of broad anti-coronavirus chemical agents for repurposing against SARS-CoV-2 and variants of concern

Gerardo Turcatti, Fabien Kuttler, Liliane Yang, Michael Bauer

Endemic human coronaviruses (hCoVs) 229E and OC43 cause respiratory disease with recurrent infections, while severe acute respiratory syndrome (SARS)-CoV-2 spreads across the world with impact on health and societies. Here, we report an image-based multicy ...

2022

Full-scale testing of European steel beams with reduced beam section under reversed cyclic loading

Dimitrios Lignos, Hiroyuki Inamasu

Steel beams with reduced beam section (RBS) are often used as part of prequalified connections in seismic regions. However, RBS connections are not as common in Europe. Reasons relate to easiness in fabrication, which requires on-site welding, and the seis ...

Springer Nature2022

The COUGHVID crowdsourcing dataset: A corpus for the study of large-scale cough analysis algorithms

David Atienza Alonso, Lara Orlandic, Tomas Teijeiro Campo

Overview Cough audio signal classification has been successfully used to diagnose a variety of respiratory conditions, and there has been significant interest in leveraging Machine Learning (ML) to provide widespread COVID-19 screening. Th ...

Zenodo2021

A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma

Didier Trono, Priscilla Turelli, Florence Pojer, Charlène Mireille Raymonde Raclot, Céline Pellaton, Valeria Cagno, Jérémy Campos

The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the serum of an individual indicates previous infection or vaccination. However, it provides limited insight into the protective nature of this immune resp ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Detection of Spatiotemporal Clusters of COVID-19-Associated Symptoms and Prevention Using a Participatory Surveillance App: Protocol for the @choum Study

Stéphane Joost, David Nicolas De Ridder, Idris Guessous

Background: The early detection of clusters of infectious diseases such as the SARS-CoV-2-related COVID-19 disease can promote timely testing recommendation compliance and help to prevent disease outbreaks. Prior research revealed the potential of COVID-19 ...

JMIR PUBLICATIONS, INC2021

Transgenic Model Systems Have Revolutionized the Study of Disease

Christopher Chase Bolt, Alexandre Gauthier Aurèle Mayran

The current pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected most of the world in a profound way. As an indirect consequence, the general public has been put into direct contact with the research process, almost ...

MARY ANN LIEBERT, INC2021

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19

Mats Julius Stensrud

In response to the coronavirus disease (COVID-19) pandemic, public health scientists have produced a large and rapidly expanding body of literature that aims to answer critical questions, such as the proportion of the population in a geographic area that h ...

2021

Group testing for connected communities

Suhas Diggavi, Christina Fragouli, Pavlos Nikolopoulos, Sundara Rajan Srinivasavaradhan

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in disjoint communities: each individual participates in a community, and its infection probability depe ...

MICROTOME PUBLISHING2021

Large variation in anti-SARS-CoV-2 antibody prevalence among essential workers in Geneva, Switzerland

Didier Trono, Francisco Javier Perez Saez, Francesco Pennacchio, Maria Eugenia Zaballa, Idris Guessous

Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, to protect workers and limit SARS-CoV-2 spread. Here, we present results from our SEROCoV- ...

Nature Research2021

Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study

Jean-Yves Meuwly, Mary-Anne Hartley

Background. Lung ultrasonography (LUS) is a promising pragmatic risk-stratification tool in coronavirus disease 2019 (COVID-19). This study describes and compares LUS characteristics between patients with different clinical outcomes. ...

OXFORD UNIV PRESS INC2021