Information derived from experiences is incorporated into the brain as changes to ensembles of cells, termed engram cells, which allow memory storage and recall. The mechanism by which those changes hold specific information is unclear. Here, we test the h ...
Virtual Memory (VM) is a critical programming abstraction that is widely used in various modern computing platforms. With the rise of datacenter computing and birth of planet-scale online services, the semantic and capacity requirements from memory have ev ...
The aim of this paper is to serve as a lightweight introduction to concurrency control for database theorists through a uniform presentation of the work on robustness against Multiversion Read Committed and Snapshot Isolation. ...
We consider the problem of training a neural network to store a set of patterns with maximal noise robustness. A solution, in terms of optimal weights and state update rules, is derived by training each individual neuron to perform either kernel classifica ...
While serializability always guarantees application correctness, lower isolation levels can be chosen to improve transaction throughput at the risk of introducing certain anomalies. A set of transactions is robust against a given isolation level if every p ...
The formation and storage of memories has been under deep investigation for several decades. Nevertheless, the precise contribution of each brain region involved in this process and the interplay between them across memory consolidation is still largely de ...
Learning and memory rely on synaptic communication in which intracellular signals are transported to the nucleus to stimulate transcriptional activation. Memory induced transcriptional increases are accompanied by alterations to the epigenetic landscape an ...
Transaction processing is a central part of most database applications. While serializability remains the gold standard for desirable transactional semantics, many database systems offer improved transaction throughput at the expense of introducing potenti ...
Short-term synaptic plasticity and modulations of the presynaptic vesicle release rate are key components of many working memory models. At the same time, an increasing number of studies suggests a potential role of astrocytes in modulating higher cognitiv ...
In this thesis, we propose model order reduction techniques for high-dimensional PDEs that preserve structures of the original problems and develop a closure modeling framework leveraging the Mori-Zwanzig formalism and recurrent neural networks. Since high ...
Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...
Memory formation and storage rely on multiple interconnected brain areas, the contribution of which varies during memory consolidation. The medial prefrontal cortex, in particular the prelimbic cortex (PL), was traditionally found to be involved in remote ...