Publications associées à Inconsistent relationship between body weight/body mass index prior to total knee arthroplasty and the 12-year survival

Surgical approaches to the capitellum: a comparative anatomic study

Alexandre Terrier, Frédéric Vauclair, Patrick Goetti

Background: Osteochondritis dissecans (OCD) of the humeral capitellum is an important cause of elbow disability in young athletes. Large and unstable lesions sometimes require joint reconstruction with osteochondral autograft. Several approaches have been ...

Mosby-Elsevier2024

White adipose tissue distribution and amount are associated with increased white matter connectivity

Jean-Philippe Thiran, Elda Fischi Gomez, Gabriel Girard, Philipp Johannes Koch, Liana Okudzhava

Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...

Wiley2024

Glenohumeral joint force prediction with deep learning

Dominique Pioletti, Alexandre Terrier, Philippe Büchler, Patrick Goetti

Deep learning models (DLM) are efficient replacements for computationally intensive optimization techniques. Musculoskeletal models (MSM) typically involve resource-intensive optimization processes for determining joint and muscle forces. Consequently, DLM ...

Elsevier Sci Ltd2024

Proteomics reveals unique plasma signatures in constitutional thinness

Loïc Dayon, Jörg Hager, Nele Gheldof

Purpose Studying the plasma proteome of control versus constitutionally thin (CT) individuals, exposed to overfeeding, may give insights into weight-gain management, providing relevant information to the clinical entity of weight-gain resistant CT, and dis ...

WILEY-V C H VERLAG GMBH2022

Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes

Olaia Maria Naveiras Torres-Quiroga, Vasco Ledebur de Antas de Campos, Josefine Catharina Pedersen Tratwal, Daniel Naveed Tavakol, Charles Christopher Bataclan

Bone marrow adipocytes (BMAds) constitute the most abundant stromal component of adult human bone marrow. Two subtypes of BMAds have been described, the more labile regulated adipocytes (rBMAds) and the more stable constitutive adipocytes (cBMAds), which d ...

FRONTIERS MEDIA SA2022

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Stéphane Joost, Idris Guessous

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

ELSEVIER SCI LTD2022

Navigation Improves the Survival Rate of Mobile-Bearing Total Knee Arthroplasty by Severe Preoperative Coronal Deformity: A Propensity Matched Case-Control Comparative Study

Brigitte Jolles-Haeberli

The primary hypothesis of this study was that the survival rate over 10 years of total knee arthroplasties (TKAs) implanted with a navigation system was superior to that of TKAs implanted with a conventional technique. The secondary hypothesis was that the ...

GEORG THIEME VERLAG KG2021

Advantages of patient-specific cutting guides with disposable instrumentation in total knee arthroplasty: a case control study

Brigitte Jolles-Haeberli

BackgroundTotal knee arthroplasty (TKA) is most frequently planned using conventional two-dimensional weight-bearing lower limb radiographs and is performed with conventional femoral and tibial cutting guides. Questions have been raised about the accuracy ...

BMC2021

A comparative surface analysis of explanted hip joint prostheses made of different biomedical alloys

Stefano Mischler, Angela Bermudez Castañeda, Adriana Esguerra Arce, Johanna Esguerra Arce

The introduction of modular design in total hip arthroplasty has enabled the use of different materials in one single configuration and the adjustment of the prosthesis to the patient's body, and facilitated medical revisions. However, modularity leads to ...

IMPRENTA UNIV ANTIOQUIA2021

Overcorrected Implants for Total Shoulder Arthroplasty

Yasmine Boulanaache

Glenohumeral osteoarthritis is a degenerative shoulder joint disease, which causes the breakdown of articular cartilage and bone. People affected by this disease suffer from severe pain and eventually reduced mobility and poor life quality. This disease is ...

EPFL2021

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Mats Julius Stensrud, Aaron Leor Sarvet

Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...

2021

Human mortality at extreme age

Anthony Christopher Davison, Léo Raymond-Belzile

We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads ...

ROYAL SOC2021

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Johan Auwerx, Evan Graehl Williams, Maroun Bou Sleiman, Pooja Jha

How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...

NATURE PORTFOLIO2021

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

Felix Naef, Nicholas Edward Phillips

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships b ...

2021

Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study

Jean-Yves Meuwly, Mary-Anne Hartley

Background. Lung ultrasonography (LUS) is a promising pragmatic risk-stratification tool in coronavirus disease 2019 (COVID-19). This study describes and compares LUS characteristics between patients with different clinical outcomes. ...

OXFORD UNIV PRESS INC2021

Real-world gait speed estimation, frailty and handgrip strength: a cohort-based study

Kamiar Aminian, Anisoara Ionescu, Abolfazl Soltani

Gait speed is a reliable outcome measure across multiple diagnoses, recognized as the 6th vital sign. The focus of the present study was on assessment of gait speed in long-term real-life settings with the aim to: (1) demonstrate feasibility in large cohor ...

Nature Portfolio2021

Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity

Kristina Schoonjans, Johan Auwerx

Sirtuin 3 (SIRT3) is a protein deacetylase regulating beta-cell function through inhibiting oxidative stress in obese and diabetic mice, but the detailed mechanism and potential effect of beta-cell-specific SIRT3 on metabolic homeostasis, and its potential ...

AMER DIABETES ASSOC2021

A Crevice Corrosion Model for Biomedical Trunnion Geometries and Surfaces Feature

Stefano Mischler, Anna Neus Igual Muñoz, Angela Bermudez Castañeda

Modular hip joint implants were introduced in arthroplasty medical procedures because they facilitate the tailoring of patients’ anatomy, the use of different materials in one single configuration, as well as medical revision. However, in certain cases, su ...

2021

No difference in 13-year survival after medial pivot or central pivot mobile bearing total knee arthroplasty. A propensity matched comparative analysis

Brigitte Jolles-Haeberli

Purpose The present study was designed to evaluate the long-term results (more than 10 years) of mobile bearing total knee arthroplasty (TKA) and to compare the survival of medial pivot axis (MPA) and central pivot axis (CPA) TKAs. The primary hypothesis w ...

2021

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy

Thierry Buclin, Monia Guidi, Jacques Fellay, Christian Hammer, Christian Axel Wandall Thorball

Objective. There is limited data on abdominal obesity and the influence of genetics on weight change after ant iretroviral therapy (ART) initiation. We assessed body mass index (BMI) and waist hip ration (WHR) change over time in the Swiss HIV Cohort study ...

OXFORD UNIV PRESS INC2020