Publication

Magneto-microfluidic three-dimensional focusing of magnetic particles

Martinus Gijs, Thomas Lehnert, Yves Moser, Rana Afshar Ghasemlouy
2010
Conference Papers

Résumé

We present a method for magneto-microfluidic three-dimensional focusing of magnetic microparticles from a dense plug into a single streamline with longitudinal inter-particle spacing. Plug formation on-chip is induced by a high-gradient magnetic field generated at the sidewall of a microchannel by an integrated micromachined magnetic tip that is connected to an external electromagnet. Controlled release of the microparticles is achieved using an exponential damping protocol of the magnetic retention force in the presence of an applied flow.

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https://infoscience.epfl.ch/entities/publication/f5e5c035-0ecb-40b8-bbad-13ad477d7919

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Martinus Gijs, Thomas Lehnert, Yves Moser, Rana Afshar Ghasemlouy
2010
Conference Papers

Résumé

Source officielle

https://infoscience.epfl.ch/entities/publication/f5e5c035-0ecb-40b8-bbad-13ad477d7919

À propos de ce résultat

Concepts associés (14)

Droplet-based microfluidics

Droplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes (μl to fl) of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments.

Microfluidique

La microfluidique est la science et la technique des systèmes manipulant des fluides et dont au moins l'une des dimensions caractéristiques est de l'ordre du micromètre. George Whitesides définit la microfluidique comme « la science et la technologie des systèmes qui manipulent de petits volumes de fluides ( à ), en utilisant des canaux de la dimension de quelques dizaines de micromètres ». Selon Patrick Tabeling, Tabeling précise qu'il entend essentiellement par « nouvelles techniques » la microfabrication héritée de la micro-électronique.

Magnetic tweezers

Magnetic tweezers (MT) are scientific instruments for the manipulation and characterization of biomolecules or polymers. These apparatus exert forces and torques to individual molecules or groups of molecules. It can be used to measure the tensile strength or the force generated by molecules. Most commonly magnetic tweezers are used to study mechanical properties of biological macromolecules like DNA or proteins in single-molecule experiments. Other applications are the rheology of soft matter, and studies of force-regulated processes in living cells.

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