Publication

More than seven decades of Acta Tropica: Looking back to move into the future

Publications associées (17)

Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles

All life forms on earth ultimately descended from a primordial population dubbed the last universal common ancestor or LUCA via Darwinian evolution. Extant living systems share two salient functional features, a metabolism extracting and transforming energ ...

2023

Novel High-Throughput Fluorescence-Based Assay for the Identification of Nematocidal Compounds That Target the Blood-Feeding Pathway

Gerardo Turcatti, Marc Chambon, Nicola Harris, Anthony Marchand, Tiffany Babette Angélique Bouchery, Mati André Marie Moyat

Hookworm infections cause a neglected tropical disease (NTD) affecting ~740 million people worldwide, principally those living in disadvantaged communities. Infections can cause high morbidity due to their impact on nutrient uptake and their need to feed o ...

2022

Plant Terpenes on Treating Cardiovascular and Metabolic Disease: A Review

Rodrigo Araujo Fraga Da Silva

The use of medicinal plants as a therapy alternative is old as human existence itself. Nowadays, the search for effective molecules for chronic diseases treatments has increased. The cardiometabolic disorders still the main cause of death worldwide and pla ...

BENTHAM SCIENCE PUBL LTD2021

Gene drives for schistosomiasis transmission control

Francisco Javier Perez Saez

Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas. Although mass drug administr ...

2019

A field-based modelling framework of the ecohydrology of schistosomiasis

Francisco Javier Perez Saez

Successful control of schistosomiasis, a water-borne parasitic disease, is challenged by the intricacy of the wormâ s lifecycle, which depends on aquatic snail intermediate hosts, and involves environmental, ecologic, and socio-economic factors. Current s ...

EPFL2018

Heterogeneity in schistosomiasis transmission dynamics

Andrea Rinaldo, Enrico Bertuzzo, Francisco Javier Perez Saez, Lorenzo Mari, Marino Gatto

Simple models of disease propagation often disregard the effects of transmission heterogeneity on the ecological and epidemiological dynamics associated with host-parasite interactions. However, for some diseases like schistosomiasis, a widespread parasiti ...

Academic Press Ltd- Elsevier Science Ltd2017

Host shift and cospeciation rate estimation from co-phylogenies

Séverine Vuilleumier Varisco

Host shifts can cause novel infectious diseases, and is a key process in diversification. Disentangling the effects of host shift vs. those of cospeciation is non-trivial as both can result in phylogenic congruence. We develop a new framework based on netw ...

Wiley2017

Genetic diversity of two Daphnia-infecting microsporidian parasites, based on sequence variation in the internal transcribed spacer region

Stefan Jean Laurent

Background: Microsporidia are spore-forming obligate intracellular parasites that include both emerging pathogens and economically important disease agents. However, little is known about the genetic diversity of microsporidia. Here, we investigated patter ...

Biomed Central Ltd2016

An epidemiological model for proliferative kidney disease in salmonid populations

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Marino Gatto, Luca Carraro

Background: Proliferative kidney disease (PKD) affects salmonid populations in European and North-American rivers. It is caused by the endoparasitic myxozoan Tetracapsuloides bryosalmonae, which exploits freshwater bryozoans and salmonids as hosts. Inciden ...

Biomed Central Ltd2016

Hydrology and density feedbacks control the ecology of intermediate hosts of schistosomiasis across habitats in seasonal climates

Andrea Rinaldo, Enrico Bertuzzo, Francisco Javier Perez Saez, Natalie Claire Ceperley, Theophile Mande, Lorenzo Mari, Marino Gatto

We report about field and theoretical studies on the ecology of the aquatic snails (Bulinus spp. and Biomphalaria pfeifferi) that serve as obligate intermediate hosts in the complex life cycle of the parasites causing human schistosomiasis. Snail abundance ...

Natl Acad Sciences2016

Institutions, Innovation and Public Health

Viviana Carolina Munoz Tellez de Kieffer

This study concerns the economics of innovation in the area of medical innovation -new diagnostics, medicines and vaccines-, and in particular how innovation contributes to meeting public health needs. Significant advances have taken place in medical scien ...

EPFL2015

A Theoretical Analysis of the Geography of Schistosomiasis in Burkina Faso Highlights the Roles of Human Mobility and Water Resources Development in Disease Transmission

Yeli Mariam Sou, Andrea Rinaldo, Enrico Bertuzzo, Francisco Javier Perez Saez, Natalie Claire Ceperley, Theophile Mande, Lorenzo Mari, Marino Gatto

We study the geography of schistosomiasis across Burkina Faso by means of a spatially explicit model of water-based disease dynamics. The model quantitatively addresses the geographic stratification of disease burden in a novel framework by explicitly acco ...

Public Library of Science2015

The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11–12th March 2015)

Melanie Blokesch, Frédérique Marie Jeanne Le Roux

Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring dur ...

Frontiers Media SA2015

Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead

Nicola Harris

The rodent intestinal nematode H.p.bakeri has played an important role in the exploration of the host–parasite relationship of chronic nematode infections for over six decades, since the parasite was first isolated in the 1950s by Ehrenford. It soon became ...

Wiley-Blackwell2014

A miniaturized continuous dielectrophoretic cell sorter and its applications

Philippe Renaud, Nicolas Demierre, Thomas Michael Braschler, Ana Valero

There is great interest in highly sensitive separation methods capable of quickly isolating a particular cell type within a single manipulation step prior to their analysis. We present a cell sorting device based on the opposition of dielectrophoretic forc ...

American Institute of Physics2010

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

Stewart Cole

Buruli ulcer is an emerging human disease caused by infection with a slow-growing pathogen, Mycobacterium ulcerans, that produces mycolactone, a cytotoxin with immunomodulatory properties. The disease is associated with wetlands in certain tropical countri ...

2008

Transnationalism and diaspora resources having an impact on development in the homelands

Gabriela Tejada Guerrero

Although migration and development are high on the international political agenda today, there is a shortage of data on diasporas in the host countries as well as a lack of information on their transnational practices and impact on the development of their ...

2008