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Ph D. in engineering– Chemical process engineer Researcher and lecturer in the field of computer aided process and energy systems engineering. Lecturer in the mechanical engineering, electrical engineering and environmental sciences engineering in EPFL. I'm responsible for the Minor in Energy of EPFL and I'm involved in 3 projects of the Competence Center in Energy and Mobility (2nd generation biofuel, Wood SOFC, and gas turbine development with CO2 mitigation) in which i'm contributing to the energy conversion system design and optimisation. Short summary of my scientific carrer After a graduation in chemical engineering from the University of Liège, I have obtained a Ph. D. from the University of Liège in the LASSC laboratory of Prof. Kalitventzeff (former president of the European working party on computer aided process engineering). This laboratory was one of the pioneering laboratory in the field of Computer Aided Process Engineering. In the group of Professor Kalitventzeff, I have worked on the development and the applications of data reconciliation, process modelling and optimisation techniques in the chemical process industry, my experience ranges from nuclear power stations to chemical plants. In the LASSC, I have been responsible from the developments in the field of rational use of energy in the industry. My first research topic has been the methodological development of process integration techniques, combining the use of pinch based methods and of mathematical programming: e.g. for the design of multiperiod heat exchanger networks or Mixed integer non linear programming techniques for the optimal management of utility systems. Fronted with applications in the industry, my work then mainly concentrated on the optimal integration of utility systems considering not only the energy requirements but the cost of the energy requirements and the energy conversion systems. I developed methods for analysing and integrating the utility system, the steam networks, combustion (including waste fuel), gas turbines or other advanced energy conversion systems (cogeneration, refrigeration and heat). The techniques applied uses operation research tools like mixed integer linear programming and exergy analysis. In order to evaluate the results of the utility integration, a new graphical method for representing the integration of the utility systems has been developed. By the use of MILP techniques, the method developed for the utility integration has been extended to handled site scale problems, to incorporate environmental constraints and reduce the water usage. This method (the Effect Modelling and Optimisation method) has been successfully applied to the chemical plants industry, the pulp and paper industry and the power plant. Instead of focusing on academic problems, I mainly developed my research based on industrial applications that lead to valuable and applicable patented results. Recently the methods developed have been extended to realise the thermoeconomic optimisation of integrated systems like fuel cells. My present R&D work concerns the application of multi-objective optimisation strategies in the design of processes and integrated energy conversion systems. Since 2001, I’m working in the Industrial Energy Systems Laboratory (LENI) of Ecole Polytechnique fédérale de Lausanne (EPFL) where I’m leading the R&D activities in the field of Computer Aided Analysis and Design of Industrial Energy Systems with a major focus on sustainable energy conversion system development using thermo-economic optimisation methodologies. A part from the application and the development of process integration techniques, that remains my major field of expertise, the applications concern : Rational use of water and energy in Industrial processes and industrial production sites : projects with NESTLE, EDF, VEOLIA and Borregaard (pulp and paper).Energy conversion and process design : biofuels from waste biomass (with GASNAT, EGO and PSI), water dessalination and waste water treatment plant (VEOLIA), power plant design (ALSTOM), Energy conversion from geothermal sources (BFE). Integrated energy systems in urban areas : together with SCANE and SIG (GE) and IEA annexe 42 for micro-cogeneration systems. I as well contributed to the definition of the 2000 Watt society and to studies concerning the emergence of green technologies on the market in the frame of the Alliance for Global Sustainability.

Lothar Helm was born in Gernsbach (Germany) in 1952. He studied physics at the University of Karlsruhe (Germany) and obtained his diploma degree in 1977. He remained in Karlsruhe for his Ph.D. research with Prof. H. G. Hertz and received his degree in physical chemistry in 1980. In 1980 he joined the laboratories of Prof. André Merbach at the University of Lausanne, Switzerland. From 1983 to 2001 he was maître d’enseignement et de recherche at the Faculty of Science of the University of Lausanne. In 2001 he moved, together with the whole chemistry department, from the University of Lausanne to the Ecole Polytechnique Fédérale de Lausanne (EPFL). Since 2006 he is adjunct professor at the Institute of Chemical Sciences and Engineering at EPFL and director of the NMR services of the institute. From 2007 to 2011 he was director of the "Conférence du corps Enseignant" at EPFL. Since 2011 he is member of the School Assembly of EPFL (AE). MAIN RESEARCH INTERESTS: • Physico-chemical studies of contrast agents for medical magnetic resonance imaging (MRI) • Study of reactivity and reaction mechanisms in coordination chemistry by variable temperature and pressure nuclear magnetic resonance • Computer simulation of solvent dynamics on cations and metal complexes in solution Professional course

Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways. Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards. Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.

André Merbach was born in Lausanne in 1940. He studied at the Polytechnical School of the University of Lausanne (Pelet and A3E2PL Awards), where he obtained in 1962 his degree in Chemical Engineering with a diploma research work in organic chemistry. In 1964, the University of Lausanne awarded him a PhD for his research on quaternary solubility systems with formation of mixed crystals. He spent then a Postdoctoral Fellowship in the Lawrence Radiation Laboratory at the University of California, Berkeley, where he studied the ionisation of strong electrolytes by NMR. Upon his return in 1965 to the Institute of Inorganic and Analytical Chemistry at the University of Lausanne, he was asked to create a research and teaching program in Coordination Chemistry. He was appointed Assistant Professor in 1971. In 1973, the Swiss Chemical Society awarded him the Werner Prize and Medal for his research on the structure, the stability and the dynamics of metal halogen adducts by NMR and, the same year, was nominated Professor of Inorganic and Analytical Chemistry. He was a member of the Swiss National Foundation for Scientific Research in the division of Mathematics, Natural Sciences and Engineering from 1985 until 1996. He represents Switzerland on the COST Chemistry Technical Committee (European Co-operation in the Field of Scientific and Technical Research: 35 countries and 1000 research groups in chemistry) and has chaired this Committee from 1998 to 2000. He was the Chairman of the Management Committee of the COST Action D6 on Chemical Processes and Reactions under Extreme or Non-Classic Conditions (1992-1997). He has organised the XXIXth International Conference in Coordination Chemistry (ICCC) in Lausanne in 1992. He has been awarded an honoris causa doctorate from the Lajos Kossuth University of Debrecen (Hungary) in 1993 for his work on elucidating reaction mechanisms in coordination chemistry utilising high pressure NMR. He has been called at the presidency of the Swiss Chemical Society (2001-2004). The University of Geneva awarded him an honoris causa doctorate in 2003.

Awards: 1999 Young Investigator Award Plenary Lectureship , International Society for Neurochemistry 2011 Fellow , ESMRMB 2011 Teaching Award , Section Sciences de la Vie, EPFL

Daniel Favrat got his Master degree in Mechanical Engineering from EPFL in 1972 and his PhD also from EPFL. He then spent 12 years in industrial research laboratories in Canada (Esso Canada) and Switzerland (CERAC: Centre Européen de Recherche Atlas Copco). From 1988 to 2013, he was full professor and director of the Industrial Energy Systems Laboratory (LENI) at EPFL. During that period he was successively director of the Institute of Energy and director of the Institute of Mechanical Engineering. From August 2013 he works at EPFL Energy Center first as director ad interim and now as director technologies. His research fields include systemic analyses accounting for energy, environment and economics (so-called environomic optimisation) and advanced conversion systems for a more rational use of energy (heat pumps &ORC, engines, fuel cells, power plants, etc). He is a member of the Swiss Academy of Engineering Sciences and of the National Academy of Technology in France. He has also an active participation in the World Federation of Engineering Organizations (WFEO) as a member of the executive committee and vice-chair of the energy committee. He is associate editor of the journal "Energy" and of International Journal of thermodynamics. He is the author of several books on thermodynamics and energy systems analysis. He is also affiliate professor at the “Royal Institute of Technology (KTH)” in Stockholm.

Pierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain. This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 – 497, 1999). He is the author of over 100 articles published in peer-reviewed journals. He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the “Functional Mapping of the Human Brain Conference”. In November 2000 he has been a “Mc Donnel Visiting Scholar” at Washington University School of Medicine. Pierre J. Magistretti is the President-Elect (2002 – 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 – 1998). Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases". POSITIONS AND HONORS MAIN POSITION HELD • 1988-2004 Professor of Physiology, University of Lausanne Medical School • 1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School • 2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School • 2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL) • 2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV) • 2007-present Chairman of the Scientific Advisory Board of Centre d’Imagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne • 2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV) • 2010-present Director, National Center for Competence in Research (NCCR) “The synaptic bases of mental diseases” of the Swiss National Science Foundation • 2010-present Secretary General, International Brain Research Organization (IBRO) MAIN HONORS AND AWARDS • 1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences • 2001 Elected Member of Academia Europaea • 2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam • 2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich • 2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008 • 2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association • 2011 Camillo Golgi Medal Award, Golgi Fondation • 2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)