Publications related to Grafting

Compliant vascular grafts and methods of use

Compliant vascular grafts for implantation in the vasculature are provided. The compliant vascular grafts are designed to expand longitudinally and radially within a blood vessel, such as an artery, and is expected to be particularly well suited for treati ...

2024

Compliance-matching vascular grafts with personalization potential

Georgios Rovas

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

EPFL2023

Architecturally Diverse Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

Sabrina Sant

Polymer brushes, which are polymers anchored to a solid substrate by one chainend, have the ability to modify the properties of an underlying substrate, offering intriguing features such as enhanced lubrication, reduced friction, colloidal stability, and a ...

EPFL2023

The response of stomatal conductance to seasonal drought in tropical forests

Charlotte Grossiord, Jin Wu

Stomata regulate CO2 uptake for photosynthesis and water loss through transpiration. The approaches used to represent stomatal conductance (g s) in models vary. In particular, current understanding of drivers of the variation in a key parameter in those mo ...

2020

A Review on Finite Element Modeling and Simulation of the Anterior Cruciate Ligament Reconstruction

Dimitar Yuriev Stanev

The anterior cruciate ligament (ACL) constitutes one of the most important stabilizing tissues of the knee joint whose rapture is very prevalent. ACL reconstruction (ACLR) from a graft is a surgery which yields the best outcome. Taking into account the com ...

FRONTIERS MEDIA SA2020

Knitted Silk-Collagen Scaffold Incorporated with Ligament Stem/Progenitor Cells Sheet for Anterior Cruciate Ligament Reconstruction and Osteoarthritis Prevention

Dominique Pioletti, Ting Zhu, Weiliang Shen, Jiayun Huang

Current surgical management of anterior cruciate ligament (ACL) rupture still remains an intractable challenge in ACL regeneration due to the weak self-healing capability of ACL. Inadequate cell numbers and vascularization within the articular cavity contr ...

2019

Polymer brush interfaces for protein biosensing prepared by surface-initiated controlled radical polymerization

Harm-Anton Klok, Mark Billing, Michael Badoux

Thin polymer films that are able to bind proteins are of great relevance for a wide variety of biosensor and biochip applications. Some of these applications require films that have high protein binding capacities while others call for surfaces that allow ...

2019

Effects of Grafting Density and Film Thickness on the Adhesion of Staphylococcus epidermidis to Poly(2-hydroxy ethyl methacrylate) and Poly(poly(ethylene glycol)methacrylate) Brushes

Harm-Anton Klok, Sorin Alexandru Ibanescu

Thin polymer films that prevent the adhesion of bacteria are of interest as coatings for the development of infection-resistant biomaterials. This study investigates the influence of grafting density and film thickness on the adhesion of Staphylococcus epi ...

Wiley-Blackwell2016

Swelling Behavior and Nanomechanical Properties of (Peptide-Modified) Poly(2-hydroxyethyl methacrylate) and Poly(poly(ethylene glycol) methacrylate) Brushes

Harm-Anton Klok, Solenne Desseaux, Kislon Voitchovsky, Nicolas Bertrand Schüwer, Juan Pablo Hinestrosa Salazar

Poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(poly(ethylene glycol) methacrylate) (PPEGMA) brushes represent a class of thin, surface-tethered polymer films that have been extensively used e.g. to generate non-biofouling surfaces or as model systems t ...

American Chemical Society2016

Oligonucleotide Immobilization and Hybridization on Aldehyde-Functionalized Poly(2-hydroxyethyl methacrylate) Brushes

Harm-Anton Klok, Tugba Bilgiç Tune

DNA biosensing requires high oligonudeotide binding capacity interface chemistries that can be tuned to maximize probe presentation as well as hybridization efficiency. This contribution investigates the feasibility of aldehyde-functionalized poly(2-hydrox ...

American Chemical Society2015

Expanding the Polymer Mechanochemistry Toolbox through Surface-Initiated Polymerization

Harm-Anton Klok

Surface-initiated polymerizations represent a versatile toolbox to generate densely grafted assemblies of chain end-tethered polymers. At sufficiently short interchain distances, surface-grafted polymers are forced into an extended chain conformation, whic ...

Amer Chemical Soc2015

Fabrication of thermo-responsive nano-valve by grafting-to in melt of poly(N-isopropylacrylamide) onto nanoporous silicon nitride membranes

Philippe Renaud, Alexandre Zenon Ivan Bojko, Raphaël Pugin, Franck Montagne

This article reports the grafting-to in melt of amino and carboxy-terminated poly(N-isopropylacrylamide) (PNIPAM) onto ultrathin nanoporous silicon nitride membranes (NSiNMs) with a mean pore size of 85 +/- 15 nm functionalized respectively with a self-ass ...

Elsevier2014

Plant functional diversity drives niche-size-structure of dominant microbial consumers along a poor to extremely rich fen gradient

Vincent Eric Jules Jassey, Bjorn Jozef Maria Robroek, Mariusz Lamentowicz

Plant community composition is recognized more and more for playing an important role in ecosystem processes, such as C cycling. In particular, plant functional type (PFT) composition seems to have a key regulatory role, yet the underlying mechanisms in ...

Wiley-Blackwell2014

Aqueous Fabrication of pH-Gated, Polymer-Brush-Modified Alumina Hybrid Membranes

Harm-Anton Klok, Caroline Sugnaux

In this Article, we studied the surface immobilization of five organic-acid-modified atom-transfer radical polymerization (ATRP) initiators based on salicylic acid, catechol, phthalic acid, and m- and p-benzoic add on alumina, and we also investigated the ...

Amer Chemical Soc2013

Surface Modification of Polyimide Thin Films for Peripheral Invasive Neural Interfaces

Silvestro Micera

Despite recognized as one key component for establishing a functional electrical connection with nerves, neural invasive peripheral interfaces are still not optimal for long-term applications in humans. An improvement in the field of biocompatible and nont ...

Asme2013

Neutron Reflectivity Study on the Postpolymerization Modification of Poly(2-hydroxyethyl methacrylate) Brushes

Harm-Anton Klok, Juan Pablo Hinestrosa Salazar

Postpolymerization modification reactions are widely employed to prepare functional polymer brushes. Relatively little is known, however, about the distribution of functional groups in such postmodified brushes. Using neutron reflectometry and UV-vis spect ...

American Chemical Society2011

A facile strategy for preparation of fluorescent SWNT complexes with high quantum yields based on ion exchange

Paul Joseph Dyson, Zhaofu Fei

The fluorescent imidazolium salt (1,3-bis(9-anthracenylmethyl)imidazolium chloride, [bamim]Cl) has been grafted onto the surfaces of single-walled carbon nanotubes (SWNTs) using an ion exchange strategy based on metathesis of the K+ ion in CO2K derivatized ...

2008

Effects of the posterior cruciate ligament reconstruction on the biomechanics of the knee joint: a finite element analysis

Alexandre Terrier

Background. Previous experimental studies have been conducted to evaluate the biomechanical effects of posterior cruciate ligament reconstruction; but no consensus has been reached on the preferred method of reconstruction. Methods. The 3D finite element m ...

2005