Publications related to Physical fitness

Metabolically enhanced CAR T cells efficiently clear solid tumors in mice

Chimeric antigen receptor (CAR) T cells in the solid tumor microenvironment enter a partially dysfunctional state called T cell exhaustion. Interleukin (IL)-10-producing CAR T cells retain their metabolic fitness, resist T cell exhaustion and display unpre ...

Nature Portfolio2024

Physiological Demands of Exergames in Older Adults- A Systematic Literature Review

Timo Markus Oskar Felder

New approaches are needed to address low physical activity levels among older adults and to promote daily physical activity tailored to their interests and abilities. This study aimed to review the current literature analyzing the physiological demands of ...

HUMAN KINETICS PUBL INC2023

Real world multimodal assessment of physical behavior change in health and disease

Gaëlle Prigent

Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...

EPFL2023

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

Automated Human Motion Analysis and Synthesis

Sena Kiciroglu

Human motion analysis and synthesis is integral to many computer vision applications, from autonomous driving to sports analysis. In this thesis, we address several problems in this domain. First we consider active viewpoint selection for pose estimation w ...

EPFL2023

Enriching the Computational Toolbox for Organocatalysis

Simone Gallarati

Organocatalysis has evolved significantly over the last decades, becoming a pillar of synthetic chemistry, but traditional theoretical approaches based on quantum mechanical computations to investigate reaction mechanisms and provide rationalizations of ca ...

EPFL2023

The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities

Jeremy Pak Hei Wong

Bacteria often engage in social interactions with neighbouring bacteria. Ecosystems which are subjected to social interactions have been widely studied in well mixed settings such as test tubes, allowing us to identify the cellular components contributing ...

EPFL2023

Genetic Algorithms for the Discovery of Homogeneous Catalysts

Rubén Laplaza Solanas, Anne-Clémence Corminboeuf, Puck Elisabeth van Gerwen, Alexandre Alain Schöpfer, Simone Gallarati

In this account, we discuss the use of genetic algorithms in the inverse design process of homogeneous catalysts for chemical transformations. We describe the main components of evolutionary experiments, specifically the nature of the fitness function to o ...

2023

Unobtrusively Regulating Children’s Posture via Slow Visual Stimuli on Tablets

Pierre Dillenbourg, Chenyang Wang, Barbara Bruno, Daniel Carnieto Tozadore

Children’s retention of a proper body posture while interacting with educational tablet applications is important for both their physical health and task performance. In this work, we propose a new approach to unobtrusively induce postural changes in child ...

Association for Computing Machinery2023

3D Pose Based Feedback For Physical Exercises

Pascal Fua, Mathieu Salzmann, Isinsu Katircioglu, Sena Kiciroglu, Ziqi Zhao, Hugues François Rémi Vinzant, Yuan Cheng, Ziyi Zhao

Unsupervised self-rehabilitation exercises and physical training can cause serious injuries if performed incorrectly. We introduce a learning-based framework that identifies the mistakes made by a user and proposes corrective measures for easier and safer ...

Springer2022

Dynamics of metabolic rate in male individuals due to the meal and regular office activities

Dolaana Khovalyg, Jiyoung Kwak

Metabolic rate is one of the main parameters affecting the thermal balance of the human body and perception of thermal comfort. Typically, we consider a constant value for a specific type of activity (sitting quiet, standing, etc.) despite the time of the ...

TU Delft2022

Interindividual variability of human thermoregulation: Toward personalized ergonomics of the indoor thermal environment

Dolaana Khovalyg

Objective The study was undertaken to show the magnitude of interindividual differences in energy expenditure (i.e., heat production) under normal living conditions with the aim of providing physiological evidence to support the advancement of a personaliz ...

WILEY2022

Geographic clusters of objectively measured physical activity and the characteristics of their built environment in a Swiss urban area

Stéphane Joost, Marco André Vieira Ruas, Idris Guessous, Cédric Gubelmann

Introduction ...

PUBLIC LIBRARY SCIENCE2022

Recent advances in fiber optic sensors for respiratory monitoring

Jiangtao Zhou, Yiping Wang, Dan Liu

There is a growing need to measure respiratory rate (RR) in a variety of applications, including in clinical and occupational settings, as well as during physical exercises. Fiber optic sensors (FOSs) is an attractive solution for wearable RR monitoring be ...

ELSEVIER SCIENCE INC2022

Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia

Johan Auwerx, Davide D'Amico, Tanes Imamura de Lima, Qi Wang, Sébastien Robert Victor Herzig, Maroun Bou Sleiman, Martin Rainer Wohlwend, Peiling Luan, Pirkka-Pekka Untamo Laurila, Barbara Moreira Crisol

Age-related muscle dysfunction and sarcopenia are major causes of physical incapacitation in older adults and currently lack viable treatment strategies. Here we find that sphingolipids accumulate in mouse skeletal muscle upon aging and that both genetic a ...

2022

Impact of adherence to a lifestyle-integrated programme on physical function and behavioural complexity in young older adults at risk of functional decline: a multicentre RCT secondary analysis

Kamiar Aminian, Anisoara Ionescu

Context Long-term adherence to physical activity (PA) interventions is challenging. The Lifestyle-integrated Functional Exercise programmes were adapted Lifestyle-integrated Functional Exercise (aLiFE) to include more challenging activities and a behaviour ...

BMJ PUBLISHING GROUP2022

Correspondence Between Values of Vertical Loading Rate and Oxygen Consumption During Inclined Running

Kamiar Aminian, Frédéric Meyer, Mathieu Pascal Falbriard, Grégoire Millet

Purpose: The aim of this study was to provide a theoretical model to predict the vertical loading rate (VLR) at different slopes and speeds during incline running. ...

SPRINGER2022

Modeling of saturated external MHD instabilities in tokamaks: A comparison of 3D free boundary equilibria and nonlinear stability calculations

Jonathan Graves

3D free boundary equilibrium computations have recently been used to model external kinks and edge harmonic oscillations (EHOs), comparing with linear MHD stability codes, and nonlinear analytic theory [Kleiner et al., Phys. Plasma Controlled Fusion 61, 08 ...

2022

Towards real-world biomechanical analysis of performance and functional capacity using wearable sensors

Salil Apte

Today, wearable heart rate monitors are an integral part of runners' training sessions, with heart rate data routinely used to assess effort intensity and stress on the body. As athletes translate their physical capacity into performance on the field throu ...

EPFL2022

Identifying a Motivational Profile for Older Adults Towards Increased Physical Activity

Pearl Pu Faltings, Yuan Lu

Personalizing behavior change (BC) strategies to motivate increased physical activity is especially important for the diverse older adult population. However, there is a lack of knowledge about how to profile older users to most effectively personalize BC ...

2021