Explores protein aggregation in neurodegenerative diseases, emphasizing the need to rethink treatment strategies and understand the role of post-translational modifications.
Explores Tau pathologies in Alzheimer's and related disorders, covering hyperphosphorylation, propagation, genetic associations, and therapeutic interventions.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Covers Parkinson's disease, its symptoms, diagnosis challenges, and current treatment options, emphasizing the need for early biomarkers and disease-modifying therapies.
Explores Parkinson's disease, covering its history, challenges in diagnosis, available treatments, neuropathological changes, and impact on motor control.
Explores beta-hairpins in polyglutamine protein aggregation, focusing on Huntington's disease and the molecular mechanisms behind toxic fibril formation.
