Publications by Jean-Luc Martin

Peripheral administration of lactate produces antidepressant-like effects

Jean-Luc Martin, Pierre Magistretti, Jean-Marie Petit, Benjamin Boury-Jamot, Maha Elsayed, Anthony Carrard

2018

Disrupting astrocyte-neuron lactate transfer persistently reduces conditioned responses to cocaine

Jean-Luc Martin, Pierre Magistretti, Benjamin Boutrel, Benjamin Boury-Jamot, Anthony Carrard

A central problem in the treatment of drug addiction is the high risk of relapse often precipitated by drug-associated cues. The transfer of glycogen-derived lactate from astrocytes to neurons is required for long-term memory. Whereas blockade of drug memo ...

Nature Publishing Group2015

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

Jean-Luc Martin, Pierre Magistretti, Igor Allaman

There is growing evidence that astrocytes are involved in the neuropathology of major depression. In particular, decreases in glial cell density observed in the cerebral cortex of individuals with major depressive disorder are accompanied by a reduction of ...

Bentham Science Publishers2013

Genes Involved in the Astrocyte-Neuron Lactate Shuttle (ANLS) Are Specifically Regulated in Cortical Astrocytes Following Sleep Deprivation in Mice

Jean-Luc Martin, Pierre Magistretti, Jean-Marie Petit, Sophie Burlet Godinot, Joël Gyger

Study Objectives: There is growing evidence indicating that in order to meet the neuronal energy demands, astrocytes provide lactate as an energy substrate for neurons through a mechanism called "astrocyte-neuron lactate shuttle" (ANLS). Since neuronal act ...

American Academy of Sleep Medicine2013

Dislocation densities and internal stress in Ni3Al

Jean-Luc Martin

Dislocation densities have been measured in Ni3Al(Hf) single crystals after deformation at various temperatures and strains. In addition, effective and athermal stresses have been determined by strain dip tests. A model is proposed for the strength anomaly ...

Taylor & Francis Ltd2013

Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes

Jean-Luc Martin, Pierre Magistretti, Igor Allaman

RATIONALE: The pharmacological actions of most antidepressants are ascribed to the modulation of serotonergic and/or noradrenergic transmission in the brain. During therapeutic treatment for major depression, fluoxetine, one of the most commonly prescribed ...

Springer Verlag2011

About the activation volume for cross-slip in Cu at high stresses

Jean-Luc Martin

The experiment performed by Bonneville and Escaig, designed for the direct measurement of the activation parameters of cross-slip, has been repeated. A denser initial dislocation forest density is obtained with a higher predeformation stress compared with ...

2011

Expression of brain-derived neurotrophic factor is not modulated by chronic mild stress in the rat hippocampus and amygdala

Jean-Luc Martin, Pierre Magistretti, Igor Allaman

Accumulating evidence supports a role for brain-derived neurotrophic factor (BDNF) in depression. However, most of these studies have been performed in animal models that have a low face validity with regard to the human disease. Here, we examined the regu ...

2009

Glide of dislocations in non-octahedral planes of fcc metals: a review

Jean-Luc Martin

In spite of frequent observations, and of sonic important consequences for industrial applications, the glide motion of dislocations in non-octahedral planes of fcc metals and alloys remains rather poorly known, and not sufficiently considered for the anal ...

2009

About the determination of the thermal and athermal stress components from stress-relaxation experiments

Jean-Luc Martin

The determination of the thermal and athermal stress components using relaxation experiments along a stress-strain curve is critically evaluated. Short-term stress-relaxations are performed along the stress-strain curve of single crystals of Ge at 850 K, C ...

2008

An appreciation of ICSMA14 on behalf of the International Committee

Jean-Luc Martin

2008

Dislocation multiplication rate in the early stage of germanium plasticity

Jean-Luc Martin, Corinne Dupas

A set of constitutive equations describing the plasticity of semiconductors is compared with the results of mechanical tests. Constant strain-rate compression tests are interrupted before the peak of the initial multiplication yield point, i.e. at the mome ...

2005