Publications by Mikaël Martino

HASPIDE: a project for the development of hydrogenated amorphous silicon radiation sensors on a flexible substrate

Giovanni De Cesare, Mikaël Martino, Sylvain Dunand, Jonathan Emanuel Thomet, Luca Massimiliano Antognini, Matthew James Large

Hydrogenated amorphous silicon (a-Si:H) is a material with a very good radiation hardness and with the possibility of deposition on flexible substrates like Polyimide (PI). Exploiting these properties, the HASPIDE (Hydrogenated Amorphous Silicon PIxels DEt ...

Iop Publishing Ltd2024

X-ray qualification of hydrogenated amorphous silicon sensors on flexible substrate

Mikaël Martino, Sylvain Dunand, Nicolas Würsch, Luca Massimiliano Antognini, Matthew James Large

Hydrogenated amorphous silicon (a-Si:H) is a well known material for its radiation resistance and for the possibility of deposition on flexible substrates like Polyimide (PI), polyethylene terephthalate (PET) or polyethylene naphthalate (PEN). Due to the p ...

IEEE2023

Gaia Data Release 2 Variable stars in the colour-absolute magnitude diagram

Stephan Morgenthaler, Mikaël Martino, Jean-Marie Petit, Shuangqing Liao

Context. The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G less than or similar to 21 mag. ...

EDP SCIENCES S A2019

Gaia Data Release 1 Open cluster astrometry: performance, limitations, and future prospects

Stephan Morgenthaler, Mikaël Martino, Shuangqing Liao

Context. The first Gaia Data Release contains the Tycho-Gaia Astrometric Solution (TGAS). This is a subset of about 2 million stars for which, besides the position and photometry, the proper motion and parallax are calculated using Hipparcos and Tycho-2 po ...

Edp Sciences S A2017

Testing parallaxes with local Cepheids and RR Lyrae stars

Stephan Morgenthaler, Mikaël Martino, Shuangqing Liao

Context. Parallaxes for 331 classical Cepheids, 31 Type II Cepheids, and 364 RR Lyrae stars in common between Gaia and the HIPPARCOS and Tycho-2 catalogues are published in Gaia Data Release 1 (DR1) as part of the Tycho-Gaia Astrometric Solution (TGAS). Ai ...

Edp Sciences S A2017

Gaia Data Release 1 Summary of the astrometric, photometric, and survey properties

Stephan Morgenthaler, Mikaël Martino, Shuangqing Liao

Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7. Aims. A summary of Gaia DR1 is presented along with illu ...

EDP Sciences2016

The Gaia mission

Stephan Morgenthaler, Mikaël Martino, Daniela Werner, Shuangqing Liao

Gaia is a cornerstone mission in the science programme of the European Space Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the ...

Edp Sciences S A2016

Design principles for therapeutic angiogenic materials

Mikaël Martino, Jeffrey Alan Hubbell, Priscilla Suhasna Maithili Briquez

Despite extensive research, pro-angiogenic drugs have failed to translate clinically, and therapeutic angiogenesis, which has potential in the treatment of various cardiovascular diseases, remains a major challenge. Physiologically, angiogenesis - the proc ...

Nature Publishing Group2016

Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing

Mikaël Martino, Jeffrey Alan Hubbell, Priscilla Suhasna Maithili Briquez

Significance: Growth factors are very promising molecules for the treatment of skin wounds. However, their translation to clinical use has been seriously limited, facing issues related to safety and cost-effectiveness. These problems may derive from the fa ...

Mary Ann Liebert, Inc2015

The TLR4 Agonist Fibronectin Extra Domain A is Cryptic, Exposed by Elastase-2; use in a fibrin matrix cancer vaccine

Mikaël Martino, Jeffrey Alan Hubbell, Alexandre de Titta, Ziad Julier, Laura Jeanbart

Fibronectin (FN) is an extracellular matrix (ECM) protein including numerous fibronectin type III (FNIII) repeats with different functions. The alternatively spliced FN variant containing the extra domain A (FNIII EDA), located between FNIII 11 and FNIII 1 ...

Nature Publishing Group2015

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

Mikaël Martino, Jeffrey Alan Hubbell, Alice Anna Tomei

With a view toward reduction of graft loss, we explored pancreatic islet transplantation within fibrin matrices rendered pro-angiogenic by incorporation of minimal doses of vascular endothelial growth factor-A165 and platelet-derived growth factor-BB prese ...

Wiley-Blackwell2015

Extracellular matrix-inspired growth factor delivery systems for bone regeneration

Mikaël Martino, Jeffrey Alan Hubbell, Priscilla Suhasna Maithili Briquez

Growth factors are very promising molecules to enhance bone regeneration. However, their translation to clinical use has been seriously limited, facing issues related to safety and cost-effectiveness. These problems derive from the vastly supra-physiologic ...

Elsevier Science Bv2015

Conjugates containing sequences from placenta growth factor and their use as components of biomaterials and in medicine

Mikaël Martino, Jeffrey Alan Hubbell, Priscilla Suhasna Maithili Briquez

Embodiments of the invention are described, including materials and methods for making molecules and materials that have a specific binding domain of a P1GF2. Embodiments include, for instance, medicaments, biomaterials, biomolecules, molecular fusions, an ...

2015

Extracellular matrix heparin-binding domains

Mikaël Martino, Jeffrey Alan Hubbell, Jeffrey James Rice, Federico Tortelli

Heparin binding peptides derived from a Tenascin (TNC) III1-5 domain or a fibrinogen ²15-66 domain have been found that bind certain cytokines with high affinity. Materials and methods for making compositions and devices using these peptides are disclosed. ...

2015

Engineering Interactions between Morphogens and the Extracellular Matrix

Mikaël Martino, Jeffrey Alan Hubbell, Priscilla Suhasna Maithili Briquez

Mary Ann Liebert, Inc2015

Therapeutic Angiogenesis by Short-Term Co-Delivery of Fibrin-Bound VEGF and PDGF-BB Proteins

Mikaël Martino, Jeffrey Alan Hubbell, Veronica Sacchi

Mary Ann Liebert, Inc2015

Engineering Interactions between Growth Factors and the Extracellular Matrix

Mikaël Martino, Jeffrey Alan Hubbell, Melody Swartz, Priscilla Suhasna Maithili Briquez, Witold Waldemar Kilarski, Esra Güç

Federation Amer Soc Exp Biol2015

Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors

Mikaël Martino, Jeffrey Alan Hubbell

In this work we have evaluated the capacity of bone morphogenetic protein-2 (BMP-2) and fibrin-binding platelet-derived growth factor-BB (PDGF-BB) to support cell growth and induce bone regeneration using two different imaging technologies to improve the u ...

Elsevier Sci Ltd2014

Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF(164)

Mikaël Martino, Jeffrey Alan Hubbell, Kristen Lorentz, Elena Groppa, Martin Ehrbar, Veronica Sacchi

Clinical trials of therapeutic angiogenesis by vascular endothelial growth factor (VEGF) gene delivery failed to show efficacy. Major challenges include the need to precisely control in vivo distribution of growth factor dose and duration of expression. Re ...

National Academy of Sciences2014

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

Mikaël Martino, Jeffrey Alan Hubbell, Melody Swartz, Stéphanie Elisabeth Metzger, Priscilla Suhasna Maithili Briquez, Witold Waldemar Kilarski, Jeffrey James Rice, Esra Güç, Federico Tortelli

Growth factors (GFs) are critical in tissue repair, but their translation to clinical use has been modest. Physiologically, GF interactions with extracellular matrix (ECM) components facilitate localized and spatially regulated signaling; therefore, we rea ...

American Association for the Advancement of Science2014