Publications by Sylvain Roy | EPFL Graph Search

Vergleich qualitativer Resultate von vier Farbsehtests der Schweizer Luftwaffe

Um das Farbsehen von Piloten- und Fluglotsenanwärtern zu testen, verwendet die Schweizer Luftwaffe 4 von der Europäischen Agentur für Flugsicherheit (EASA) zugelassene Farbsehtests: die pseudoisochromatischen Ishiharaplatten, den Spectrolux Lampentest, das ...

Georg Thieme Verlag KG2025

Efficacy and Safety of an Adjustable Glaucoma Drainage Device (eyeWatch System) for Refractory Glaucoma: A 2-Year Prospective Study

Sylvain Roy

Precis: In this study, we report a 2-year follow-up after implantation of an adjustable glaucoma drainage device combined with a novel orbital filtering plate. The IOP was efficiently controlled postoperatively with limited complications and an excellent s ...

LIPPINCOTT WILLIAMS & WILKINS2024

MRI after successful eyeWatch(TM) implantation

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin

The eyeWatch(TM) is a new glaucoma drainage device that includes an adjustable mechanism that can vary the resistance to aqueous humor outflow during the postoperative period to reduce the burden of postoperative intraocular pressure (IOP) management. The ...

SAGE PUBLICATIONS LTD2020

Comparison Between the eyeWatch Device and the Ahmed Valve in Refractory Glaucoma

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler, Constantinos Stergiopulos

Purpose: To assess the efficacy and safety of a glaucoma procedure to control intraocular pressure (IOP) using the adjustable eyeWatch glaucoma drainage device compared with Ahmed glaucoma valve (AGV) in refractory glaucoma. Patients and Methods: Monocentr ...

LIPPINCOTT WILLIAMS & WILKINS2020

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study

André Mermoud, Sylvain Roy

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma. Patients and Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma w ...

2020

Initial Clinical Results of the eyeWatch: a New Adjustable Glaucoma Drainage Device Used in Refractory Glaucoma Surgery

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler, Constantinos Stergiopulos

Precis: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted ...

LIPPINCOTT WILLIAMS & WILKINS2019

Genetic cartography of longevity in humans and mice: Current landscape and horizons

Sylvain Roy, Johan Auwerx, Evan Graehl Williams, Maroun Bou Sleiman

2018

Results of CO2 Laser-assisted Deep Sclerectomy as Compared With Conventional Deep Sclerectomy

André Mermoud, Sylvain Roy

Purpose: To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. Materials and Methods: Patients who underwent primary ...

Lippincott, Williams & Wilkins2016

Eyewatch, an Innovative Adjustable GDD for the Treatment of Glaucoma - in Vivo Results

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE: To report the in vivo results of a continuously adjustable glaucoma drainage device (GDD) in glaucoma surgery with rabbits. METHODS: Under general anesthesia, the AGDD was implanted on 12 white New-Zealand rabbits for duration of 6 months. The adj ...

Springer2016

A New Adjustable Glaucoma Drainage Device

Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. This work is focused on the testing of a new experimental noninvasively adjustable glaucoma drainage device (AGDD) that allows for the control of its outflow resistance to modulate intraocular pressure (IOP) in a customized fashion. METHODS. Six A ...

Association for Research in Vision and Ophthalmology2014

In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. We report on the in vivo testing of a novel noninvasively adjustable glaucoma drainage device (AGDD), which features an adjustable outflow resistance, and assess the safety and efficiency of this implant. METHODS. Under general anesthesia, the AGD ...

Association for Research in Vision and Ophthalmology2014

3D simulation of the aqueous flow in the human eye

Nikolaos Stergiopoulos, Philippe Reymond, Sylvain Roy, Adan Villamarin, Reda Hasballa, Orestis Vardoulis

Glaucoma results in an increase in the resistance of the aqueous humor outflow, which in turn leads to an increase of the intraocular pressure (IOP). Several treatments are proposed to reduce and stabilize the IOP that include medications, filtering surger ...

Elsevier Sci Ltd2012

Experimental characterization of the distribution of collagen fiber recruitment

Nikolaos Stergiopoulos, Christophe Boss, Sylvain Roy

The passive biomechanical behavior of blood vessels is generally modeled by a parallel arrangement of elastin and collagen, with collagen recruitment depending on vessel strain. We experimentally determined the collagen recruitment distribution using confo ...

2010

Deep sclerectomy with the Ex-PRESS X-200 implant for the surgical treatment of glaucoma

André Mermoud, Sylvain Roy

Springer, Springer Netherlands2010

Arterial biomechanics after destruction of cytoskeleton by Cytochalasin D

Nikolaos Stergiopoulos, Paolo Silacci, Sylvain Roy, Tyler Nerton Thacher

Vascular smooth muscle is a major structural element of the arterial wall. We examined the effects of cytoskeleton destruction, after administration of Cytochalasin D, on the biomechanical properties of porcine common carotids. Compared to untreated, maxim ...

2009

Biocompatibility of an x-shaped zirconium implant in deep sclerectomy in rabbits

André Mermoud, Sylvain Roy

Springer, Springer-Verlag2008

Vascular physiology : effects of vascular smooth muscle alteration on arterial wall biomechanics

Sylvain Roy

This thesis aims at better understanding the role played by vascular smooth muscle cells (VSM) in the biomechanics of the arterial wall. Current models assume that under maximal vasodilation VSM carry no load, or the so-called "active stress" is zero. Biom ...

EPFL2008

Endothelialization Of Decellularized Porcine Arteries

Nikolaos Stergiopoulos, Paolo Silacci, Sylvain Roy

2008

On the in-series and in-parallel contribution of elastin assessed by a structure-based biomechanical model of the arterial wall

Nikolaos Stergiopoulos, Sylvain Roy, Gilles Prod'Hom, Alkiviadis Tsamis

Earlier experimental work on decellularized arteries revealed the existence of significant residual stresses within the arterial wall, which are released upon chemical removal of vascular smooth muscle in normal arteries causing substantial radial expansio ...

2008

Effect of elastin degradation on carotid wall mechanics as assessed by a constituent-based biomechanical model

Nikolaos Stergiopoulos, Luca Augsburger, Sylvain Roy, Edouard Fonck, Gilles Prod'Hom

Arteries display a nonlinear anisotropic behavior dictated by the elastic properties and structural arrangement of its main constituents, elastin, collagen, and vascular smooth muscle. Elastin provides for structural integrity and for the compliance of the ...

2007