Publications by Jean-Marie Petit

Gaia Data Release 2 Variable stars in the colour-absolute magnitude diagram

Stephan Morgenthaler, Mikaël Martino, Jean-Marie Petit, Shuangqing Liao

Context. The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G less than or similar to 21 mag. ...

EDP SCIENCES S A2019

Inadequate Brain Glycogen or Sleep Increases Spreading Depression Susceptibility

Pierre Magistretti, Jean-Marie Petit

2018

Peripheral administration of lactate produces antidepressant-like effects

Jean-Luc Martin, Pierre Magistretti, Jean-Marie Petit, Benjamin Boury-Jamot, Maha Elsayed, Anthony Carrard

2018

Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression

Pierre Magistretti, Jean-Marie Petit, Benjamin Boutrel, Daniel Sciarra, Jean-René Cardinaux

Obesity and depression are major public health concerns, and there is increasing evidence that they share etiological mechanisms. CREB-regulated transcription coactivator 1 (CRTC1) participates in neurobiological pathways involved in both mood and energy b ...

Springer Nature2017

Lack of PTG involvement in glycogen regulation during sleep deprivation in mice

Pierre Magistretti, Igor Allaman, Jean-Marie Petit, Gabriele Grenningloh, Sophie Burlet Godinot, Evelyne Ruchti, Jin Teng Chung

Wiley2017

Regulation Of Neuron-Astrocyte Metabolic Coupling Across The Sleep-Wake Cycle

Pierre Magistretti, Jean-Marie Petit

Over the last thirty years, a growing number of studies showed that astrocytes play a pivotal role in the energy support to synapses. More precisely, astrocytes adjust energy production to neuronal energy needs through different mechanisms grouped under th ...

Elsevier2016

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Sleep is viewed as a fundamental restorative function of the brain, but its specific role in neural energy budget remains poorly understood. Sleep deprivation dampens brain energy metabolism and impairs cognitive functions. Intriguingly, sleep fragmentatio ...

Wiley-Blackwell2016

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive performance is well documented, the effects of long-term SF on electroencephalogra ...

American Academy of Sleep Medicine2015

Glycogen metabolism and the homeostatic regulation of sleep

Pierre Magistretti, Igor Allaman, Jean-Marie Petit, Sophie Burlet Godinot

In 1995 Benington and Heller formulated an energy hypothesis of sleep centered on a key role of glycogen. It was postulated that a major function of sleep is to replenish glycogen stores in the brain that have been depleted during wakefulness which is asso ...

Springer Verlag2015

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

Pierre Magistretti, Pascal Jourdain, Igor Allaman, Jean-Marie Petit, Gabriele Grenningloh, Evelyne Ruchti, Jiangyan Yang

L-lactate is a product of aerobic glycolysis that can be used by neurons as an energy substrate. Here we report that in neurons L-lactate stimulates the expression of synaptic plasticity-related genes such as Arc, c-Fos, and Zif268 through a mechanism invo ...

National Academy of Sciences2014

Genes Involved in the Astrocyte-Neuron Lactate Shuttle (ANLS) Are Specifically Regulated in Cortical Astrocytes Following Sleep Deprivation in Mice

Jean-Luc Martin, Pierre Magistretti, Jean-Marie Petit, Sophie Burlet Godinot, Joël Gyger

Study Objectives: There is growing evidence indicating that in order to meet the neuronal energy demands, astrocytes provide lactate as an energy substrate for neurons through a mechanism called "astrocyte-neuron lactate shuttle" (ANLS). Since neuronal act ...

American Academy of Sleep Medicine2013

The psychostimulant modafinil enhances gap junctional communication in cortical astrocytes

Pierre Magistretti, Jean-Marie Petit, Joël Gyger, Xinhe Liu

Sleep wake cycle is characterized by changes in neuronal network activity. However, for the last decade there is increasing evidence that neuroglial interaction may play a role in the modulation of sleep homeostasis and that astrocytes have a critical impa ...

Elsevier2013

Lactate as a signaling molecule for the regulation of plasticity-related genes expression

Pierre Magistretti, Pascal Jourdain, Igor Allaman, Jean-Marie Petit, Gabriele Grenningloh, Evelyne Ruchti, Jiangyan Yang

Wiley-Blackwell2013

Lactate Modifies Neuronal Excitability Through Both Nmda And Katp Receptors: Importance For Plasticity Genes Expression

Pierre Magistretti, Pascal Jourdain, Igor Allaman, Jean-Marie Petit, Gabriele Grenningloh, Evelyne Ruchti, Jiangyan Yang

Wiley-Blackwell2013

Perturbation Of Sleep-Wake Cycle Affects Astroglial Networking

Pierre Magistretti, Jean-Marie Petit

Wiley-Blackwell2013

Circadian Variations Of Gene Expression Related To Neuro-Metabolic Coupling In Astrocytes Of Anterior And Posterior Hypothalamus Of The Mice

Pierre Magistretti, Jean-Marie Petit, Joël Gyger

Wiley-Blackwell2013

Lactate As A Signaling Molecule For The Regulation Of Plasticity-Related Genes Expression

Pierre Magistretti, Pascal Jourdain, Igor Allaman, Jean-Marie Petit, Gabriele Grenningloh, Evelyne Ruchti, Jiangyan Yang

Wiley-Blackwell2013

Astrocytes display different pattern of gene expression related to neuro-metabolic coupling in anterior and posterior hypothalamus of mice

Pierre Magistretti, Jean-Marie Petit, Joël Gyger, Anna Mikhaleva

Wiley-Blackwell2012

Regulation of astrocytic connexins following sleep deprivation in mice

Pierre Magistretti, Jean-Marie Petit, Joël Gyger

Wiley-Blackwell2012

Altered Glycogen Metabolism in Cultured Astrocytes from Mice with Chronic Glutathione Deficit; Relevance for Neuroenergetics in Schizophrenia

Pierre Magistretti, Igor Allaman, Jean-Marie Petit, Kim Do

Neurodegenerative and psychiatric disorders including Alzheimer's, Parkinson's or Huntington's diseases and schizophrenia have been associated with a deficit in glutathione (GSH). In particular, a polymorphism in the gene of glutamate cysteine ligase modul ...

Public Library of Science2011