Christophe Bovigny

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Related publications (6)

Detection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated server

Matteo Dal Peraro, Christophe Bovigny, Luciano Andres Abriata

Background: Protein variability can now be studied by measuring high-resolution tolerance-to-substitution maps and fitness landscapes in saturated mutational libraries. But these rich and expensive datasets are typically interpreted coarsely, restricting d ...

2016

Detection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated server(vol 1, 242, 2016)

Matteo Dal Peraro, Christophe Bovigny, Luciano Andres Abriata

2016

Lipid Builder: A Framework To Build Realistic Models for Biological Membranes

Thomas Lemmin, Matteo Dal Peraro, Christophe Bovigny, Nicolas Grégoire Maïno, Giorgio Elikem Tamo

The physical and chemical characterization of biological membranes is of fundamental importance for understanding the functional role of lipid bilayers in shaping cells and organelles, steering vesicle trafficking and promoting membrane-protein signaling. ...

Amer Chemical Soc2015

New models and techniques to simulate realistic biological membranes

Christophe Bovigny

EPFL2014

Reaction Mechanism and Catalytic Fingerprint of Allantoin Racemase

Matteo Thomas Degiacomi, Thomas Lemmin, Matteo Dal Peraro, Marco Stenta, Christophe Bovigny

The stereospecific oxidative decomposition of urate into allantoin is the core of purine catabolism in many organisms. The spontaneous decomposition of upstream intermediates and the nonenzymatic racemization of allantoin lead to an accumulation of (R)-all ...

Amer Chemical Soc2014

Cardiolipin Models for Molecular Simulations of Bacterial and Mitochondrial Membranes

Thomas Lemmin, Diane Virginie Marie Lançon, Matteo Dal Peraro, Christophe Bovigny

Present in bacterial and mitochondrial membranes, cardiolipins have a unique dimeric structure, which carries up to two charges (i.e., one per phosphate group) and, under physiological conditions, can be unprotonated or singly protonated. Exhaustive models ...

Amer Chemical Soc2013

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