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Silvestro Micera

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Related publications (314)

Wearable Robotics for Impaired Upper-Limb Assistance and Rehabilitation: State of the Art and Future Perspectives

Despite more than thirty-five years of research on wearable technologies to assist the upper-limb and a multitude of promising preliminary results, the goal of restoring pre-impairment quality of life of people with physical disabilities has not been fully ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Neuromuscular electrical stimulation restores upper limb sensory-motor functions and body representations in chronic stroke survivors

Olaf Blanke, Silvestro Micera, Andrea Crema, Andrea Serino, Michela Bassolino, Maria Colombo

2022

Body and peripersonal space representations in chronic stroke patients with upper limb motor deficits

Olaf Blanke, Silvestro Micera, Andrea Crema, Andrea Serino, Elisa Canzoneri, Michela Bassolino, Matteo Franza

The continuous stream of multisensory information between the brain and the body during body-environment interactions is crucial to maintain the updated representation of the perceived dimensions of body parts (metric body representation) and the space aro ...

OXFORD UNIV PRESS2022

Wireless neuromodulation with porous silicon

Silvestro Micera

Wireless optoelectronic devices are fabricated by controlling the porosity of p-type silicon, enabling in vivo efficient, non-genetic optoelectronic modulation of peripheral nerve activity. ...

NATURE PORTFOLIO2022

Polysaccharide Layer-by-Layer Coating for Polyimide-Based Neural Interfaces

Silvestro Micera

Implantable flexible neural interfaces (IfNIs) are capable of directly modulating signals of the central and peripheral nervous system by stimulating or recording the action potential. Despite outstanding results in acute experiments on animals and humans, ...

MDPI2022

Neurocognitive and motor-control challenges for the realization of bionic augmentation

Silvestro Micera

Robotic fingers and arms that augment the motor abilities of non-disabled individuals are increasingly feasible yet face neurocognitive barriers and hurdles in efferent motor control. ...

NATURE PORTFOLIO2022

Predicting visual stimuli from cortical response recorded with widefield imaging in a mouse

Silvestro Micera, Daniela De Luca

Optic nerve stimulation holds great potential for visual prostheses. Its effectiveness depends on the stimulation protocol, which can be optimized to achieve cortical activation similar to that evoked in response to visual stimuli. To identify a target cor ...

IEEE2022

Disruption of layer-specific visual processing in a model of focal neocortical epilepsy

Silvestro Micera, Matteo Vissani

The epileptic brain is the result of a sequence of events transforming normal neuronal populations into hyperexcitable networks supporting recurrent seizure generation. These modifications are known to induce fundamental alterations of circuit function and ...

OXFORD UNIV PRESS INC2022

A method to establish functional vagus nerve topography from electro-neurographic spontaneous activity

Silvestro Micera, Simone Romeni

Bioelectronic medicine is an emerging approach to treat many types of diseases via electrical stimulation of the autonomic nervous system (ANS). Because the vagus nerve (VN) is one of the most important nerves controlling several ANS functions, stimulation ...

2022

Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

Stéphanie Lacour, Florent-Valéry Coen, Silvestro Micera, Grégoire Courtine, Selin Anil, Quentin Barraud, Newton Cho, Nicholas David James

Numerous neurorehabilitative, neuroprosthetic, and repair interventions aim to address the consequences of upper limb impairments after neurological disorders. Although these therapies target widely different mechanisms, they share the common need for a pr ...

AMER ASSOC ADVANCEMENT SCIENCE2022

Combining robotics with enhanced serotonin-driven cortical plasticity improves post-stroke motor recovery

Marco Mainardi, Silvestro Micera, Sara Conti, Maria Pasquini, Stefano Lai

Despite recent progresses in robotic rehabilitation technologies, their efficacy for post-stroke motor recovery is still limited. Such limitations might stem from the insufficient enhancement of plasticity mechanisms, crucial for functional recovery. Here, ...

PERGAMON-ELSEVIER SCIENCE LTD2021

A modular strategy for next-generation upper-limb sensory-motor neuroprostheses

Solaiman Shokur, Giuseppe Schiavone, Silvestro Micera

Neuroprosthetics is a discipline that aims at restoring lost functions to people affected by a variety of neurological disorders or neuro-traumatic lesions. It combines the expertise of computer science and electrical, mechanical, and micro/nanotechnology ...

ELSEVIER2021

A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

2021

Computational model of the dorsal horn circuitry for innocuous touch

Silvestro Micera, Simone Romeni

Providing a naturalistic tactile sensory feedback is currently one of the key challenges in neuroprosthetics. Modeling has played a fundamental role in the development of "biomimetic" stimulation protocols, determining optimal activation patterns to be eli ...

IEEE2021

Compliant peripheral nerve interfaces

Stéphanie Lacour, Silvestro Micera, Outman Akouissi, Valentina Marie Paggi

Peripheral nerve interfaces (PNIs) record and/or modulate neural activity of nerves, which are responsible for conducting sensory-motor information to and from the central nervous system, and for regulating the activity of inner organs. PNIs are used both ...

IOP PUBLISHING LTD2021

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

Silvestro Micera, Ivo Strauss

Bioelectronic medicine (BM) is an emerging new approach for developing novel neuromodulation therapies for pathologies that have been previously treated with pharmacological approaches. In this review, we will focus on the neuromodulation of autonomic nerv ...

IOP PUBLISHING LTD2021

Current Solutions and Future Trends for Robotic Prosthetic Hands

Solaiman Shokur, Silvestro Micera, Vincent Alexandre Mendez, Francesco Iberite

The desire for functional replacement of a missing hand is an ancient one. Historically, humans have replaced a missing limb with a prosthesis for cosmetic, vocational, or personal autonomy reasons. The hand is a powerful tool, and its loss causes severe p ...

ANNUAL REVIEWS2021

Bayesian optimization of peripheral intraneural stimulation protocols to evoke distal limb movements

Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Silvestro Micera, Grégoire Courtine, Simon Borgognon

Objective. Motor neuroprostheses require the identification of stimulation protocols that effectively produce desired movements. Manual search for these protocols can be very time-consuming and often leads to suboptimal solutions, as several stimulation pa ...

IOP Publishing Ltd2021

Brain network modulation in transradial amputee with finger perception restored through biomimetic intraneural stimulation

Fabrizio Vecchio, Silvestro Micera, Giacomo Valle

Introduction/aims The hand is a sophisticated tool which allows humans to interact with the external world mainly via the sense of touch. Previous evidences demonstrated that electrical stimulations of the nerve trunks governing the hand are able to restor ...

SPRINGER-VERLAG ITALIA SRL2021

Counteracting Balance Loss in Transfemoral Amputees by Using an Active Pelvis Orthosis: A Case Series

Silvestro Micera

This case series study was designed to provide an overview of the efficacy of an active pelvis orthosis (APO) against the fall risk after multidirectional slippages in transfemoral amputees (TFA). To achieve this goal, we investigated the dynamic stability ...

Springer Nature2021

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