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Silvestro Micera

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Related publications (314)

Implantable Fiber Bragg Grating Sensor for Continuous Heart Activity Monitoring: Ex-Vivo and In-Vivo Validation

Continuous and reliable cardiac function monitoring could improve medication adherence in patients at risk of heart failure. This work presents an innovative implantable Fiber Bragg Grating-based soft sensor designed to sense mechanical cardiac activity. T ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Silvestro Micera, Marco Bonizzato

A spinal cord injury usually spares some components of the locomotor circuitry. Deep brain stimulation (DBS) of the midbrain locomotor region and epidural electrical stimulation of the lumbar spinal cord (EES) are being used to tap into this spared circuit ...

Nature Research2021

All-Polymer Printed Low-Cost Regenerative Nerve Cuff Electrodes

Silvestro Micera

Neural regeneration after lesions is still limited by several factors and new technologies are developed to address this issue. Here, we present and test in animal models a new regenerative nerve cuff electrode (RnCE). It is based on a novel low-cost fabri ...

FRONTIERS MEDIA SA2021

Surgical Access And Stimulation Of Pudendal Nerve In Pigs To Restore The Micturition Control

Silvestro Micera, Ivo Strauss

WILEY2021

Stimulus evoked causality estimation in stereo-EEG

Silvestro Micera, Fiorenzo Artoni

Objective. Stereo-electroencephalography (SEEG) has recently gained importance in analyzing brain functions. Its high temporal resolution and spatial specificity make it a powerful tool to investigate the strength, direction, and spectral content of brain ...

IOP PUBLISHING LTD2021

Reactive Exercises with Interactive Objects: Interim Analysis of a Randomized Trial on Task-Driven NMES Grasp Rehabilitation for Subacute and Early Chronic Stroke Patients

Silvestro Micera, Andrea Crema, Flavio Raschella, Ivan Furfaro

Enriched environments and tools are believed to promote grasp rehabilitation after stroke. We designed S2, an interactive grasp rehabilitation system consisting of smart objects, custom orthoses for selective grasp constraining, and an electrode array syst ...

MDPI2021

Combining Optogenetic Stimulation and Motor Training Improves Functional Recovery and Perilesional Cortical Activity

Silvestro Micera, Francesco Saverio Pavone, Maria Pasquini

Background. An ischemic stroke is followed by the remapping of motor representation and extensive changes in cortical excitability involving both hemispheres. Although stimulation of the ipsilesional motor cortex, especially when paired with motor training ...

SAGE PUBLICATIONS INC2021

Computational approaches to decode grasping force and velocity level in upper-limb amputee from intraneural peripheral signals

Silvestro Micera, Ivo Strauss, Giacomo Valle

Objective. Recent results have shown the potentials of neural interfaces to provide sensory feedback to subjects with limb amputation increasing prosthesis usability. However, their advantages for decoding motor control signals over current methods based o ...

IOP Publishing Ltd2021

Uncontrolled manifold analysis of the effects of a perturbation-based training on the organization of leg joint variance in cerebellar ataxia

Silvestro Micera

Walking patterns of persons affected by cerebellar ataxia (CA) are characterized by wide stride-to-stride variability ascribable to: the background pathology-related sensory-motor noise; the motor redundancy, i.e., an excess of elemental degrees of freedom ...

SPRINGER2021

Connectivity Measures Differentiate Cortical and Subcortical Sub-Acute Ischemic Stroke Patients

Silvestro Micera, Michael Lassi

Brain lesions caused by cerebral ischemia lead to network disturbances in both hemispheres, causing a subsequent reorganization of functional connectivity both locally and remotely with respect to the injury. Quantitative electroencephalography (qEEG) meth ...

FRONTIERS MEDIA SA2021

Intrafascicular peripheral nerve stimulation produces fine functional hand movements in primates

Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Silvestro Micera, Grégoire Courtine, Evgenia Vladimirova Roussinova, Simon Borgognon

Restoring dexterous hand control is critical for people with paralysis. Approaches based on surface or intramuscular stimulation provide limited finger control, generate insufficient force to recover functional movements, and require numerous electrodes. H ...

AMER ASSOC ADVANCEMENT SCIENCE2021

A Software Tool for the Real-Time in Vivo Evaluation of Neural Electrodes' Selectivity

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Daniela De Luca

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

IEEE2021

Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals

Silvestro Micera, Ivo Strauss, Simone Romeni

Objective. Bioelectronic medicine is opening new perspectives for the treatment of some major chronic diseases through the physical modulation of autonomic nervous system activity. Being the main peripheral route for electrical signals between central nerv ...

IOP PUBLISHING LTD2021

Adaptation and Optimization of an Intraneural Electrode to Interface with the Cervical Vagus Nerve

Silvestro Micera, Ivo Strauss

The modulation of the cervical vagus nerve (VN) using neural electrodes has shown great potential to treat cardiovascular, inflammatory, intestinal, or respiratory dysfunctions. Intraneural electrodes have shown great potentials for other neuroprosthetic a ...

IEEE2021

Deep Learning with Convolutional Neural Network for Proportional Control of Finger Movements from surface EMG Recordings

Silvestro Micera, Vincent Alexandre Mendez, Leonardo Pollina, Fiorenzo Artoni

The control of robotic prosthetic hands (RPHs) for upper limb amputees is far from optimal. Simultaneous and proportional finger control of a RPH based on EMG signals is still challenging. Based on EMG and kinematics recordings of subjects following a pre- ...

IEEE2021

Repeated exposure to tripping like perturbations elicits more precise control and lower toe clearance of the swinging foot during steady walking

Silvestro Micera

Controlling minimum toe clearance (MTC) is considered an important factor in preventing tripping. In the current study, we investigated modifications of neuro-muscular control underlying toe clearance during steady locomotion induced by repeated exposure t ...

ELSEVIER2021

Immersive virtual reality interferes with default head-trunk coordination strategies in young children

Jenifer Cléa Miehlbradt, Silvestro Micera

The acquisition of postural control is an elaborate process, which relies on the balanced integration of multisensory inputs. Current models suggest that young children rely on an 'en-block' control of their upper body before sequentially acquiring a segme ...

Nature Portfolio2021

Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts

Silvestro Micera, Matteo Vissani

Excessive beta-band oscillations in the subthalamic nucleus are key neural features of Parkinson's disease. Yet the distinctive contributions of beta low and high bands, their dependency on striatal dopamine, and their correlates with movement kinematics a ...

NATURE RESEARCH2021

Analysis system and method for analysing the movement of a portion of the body and/or of a human prosthesis

Silvestro Micera, Andrea Crema, Fiorenzo Artoni

An analysis method (200) for analysing the pressure exerted by a portion of the body and/or of a human prosthesis comprises the following steps: sampling data generated by the portion of the body and/or the human prosthesis during a threshold calibration p ...

2021

Material surface detection on various body parts: a preliminary study for temperature substitution for upper arm amputees

Solaiman Shokur, Silvestro Micera

Experiments have shown that healthy subjects can detect materials solely relying on the material's thermal properties at their fingertip. We are interested in developing a non-invasive temperature display for sensory substitution for patients with arm ampu ...

IEEE2021

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