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Daniel Kenneth Bonner

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

Jeffrey Alan Hubbell, Melody Swartz, Alexandre de Titta, Sachiko Hirosue, Daniel Kenneth Bonner

Background: Newborns display distinct immune responses, leaving them vulnerable to infections and impairing immunization. Targeting newborn dendritic cells (DCs), which integrate vaccine signals into adaptive immune responses, might enable development of a ...

2017

Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses

Jeffrey Alan Hubbell, Melody Swartz, Sachiko Hirosue, Marcela Rincón-Restrepo, Sylvie Hauert, Daniel Kenneth Bonner, Edward Allen Phelps, Aaron Mayer

Nanoparticle delivery systems are known to enhance the immune response to soluble antigens (Ags) and are thus a promising tool for the development of new vaccines. Our laboratory has engineered two different nanoparticulate systems in which Ag is either en ...

Elsevier Sci Ltd2017

A Cationic Micelle Complex Improves CD8+T Cell Responses in Vaccination Against Unmodified Protein Antigen

Jeffrey Alan Hubbell, Melody Swartz, Davide Demurtas, Vasiliki Panagiotou, Carrie Ellen Brubaker, Daniel Kenneth Bonner

Nanoscale carrier platforms promote immune responses to vaccination by facilitating delivery of vaccine components to immunologically relevant sites. The technique is particularly valuable for subunit vaccination, in which coadministration of immunostimula ...

Amer Chemical Soc2016