Publications related to The upper limit of cardiorespiratory fitness associated with longevity: an update

Real world multimodal assessment of physical behavior change in health and disease

Sedentary lifestyle is currently considered a global pandemic, associated with major health problems such as cardiovascular disease and premature death. Regular physical activity (PA) is one way to address this problem, as it brings a variety of health ben ...

EPFL2023

Physiological Demands of Exergames in Older Adults- A Systematic Literature Review

Timo Markus Oskar Felder

New approaches are needed to address low physical activity levels among older adults and to promote daily physical activity tailored to their interests and abilities. This study aimed to review the current literature analyzing the physiological demands of ...

HUMAN KINETICS PUBL INC2023

Automated Human Motion Analysis and Synthesis

Sena Kiciroglu

Human motion analysis and synthesis is integral to many computer vision applications, from autonomous driving to sports analysis. In this thesis, we address several problems in this domain. First we consider active viewpoint selection for pose estimation w ...

EPFL2023

Dynamics of metabolic rate in male individuals due to the meal and regular office activities

Dolaana Khovalyg, Jiyoung Kwak

Metabolic rate is one of the main parameters affecting the thermal balance of the human body and perception of thermal comfort. Typically, we consider a constant value for a specific type of activity (sitting quiet, standing, etc.) despite the time of the ...

TU Delft2022

Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia

Johan Auwerx, Maroun Bou Sleiman, Peiling Luan, Davide D'Amico, Pirkka-Pekka Untamo Laurila, Martin Rainer Wohlwend, Sébastien Robert Victor Herzig, Tanes Imamura de Lima, Qi Wang, Barbara Moreira Crisol

Age-related muscle dysfunction and sarcopenia are major causes of physical incapacitation in older adults and currently lack viable treatment strategies. Here we find that sphingolipids accumulate in mouse skeletal muscle upon aging and that both genetic a ...

2022

Geographic clusters of objectively measured physical activity and the characteristics of their built environment in a Swiss urban area

Stéphane Joost, Cédric Gubelmann, Marco André Vieira Ruas, Idris Guessous

Introduction ...

PUBLIC LIBRARY SCIENCE2022

Towards real-world biomechanical analysis of performance and functional capacity using wearable sensors

Salil Apte

Today, wearable heart rate monitors are an integral part of runners' training sessions, with heart rate data routinely used to assess effort intensity and stress on the body. As athletes translate their physical capacity into performance on the field throu ...

EPFL2022

Identifying a Motivational Profile for Older Adults Towards Increased Physical Activity

Pearl Pu Faltings, Yuan Lu

Personalizing behavior change (BC) strategies to motivate increased physical activity is especially important for the diverse older adult population. However, there is a lack of knowledge about how to profile older users to most effectively personalize BC ...

2021

Activities, Housing Situation and Other Factors Influencing Psychological Strain Experienced During the First COVID-19 Lockdown in Switzerland

Garance Clément, Anna Pagani, Claudia Rebeca Binder Signer, Livia Bianca Fritz, Ralph Hansmann

Background: The Coronavirus disease 2019 (COVID-19) crisis and the corresponding first nationwide lockdown from mid-March to 10 May 2020 engendered considerable psychological strain among people in Switzerland. This study analyzes determinants of changes i ...

Frontiers Media2021

Wearable multifunctional sweat-sensing system for efficient healthcare monitoring

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nicolò Oliva, Mandresy Ivan Ny Hanitra, Francesca Criscuolo, Simone Aiassa

Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...

2020

Transient vitamin B5 starving improves mammalian cell homeostasis and protein production

Nicolas Mermod

Maintaining a metabolic steady state is essential for an organism's fitness and survival when confronted with environmental stress, and metabolic imbalance can be reversed by exposing the organism to fasting. Here, we attempted to apply this physiological ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

Wearable multi-electrode platform for ion sensing

Francesca Criscuolo

With the growth of personalized medicine and e-Health, there has been an increasing interest in the development of accurate sensing systems able to support this healthcare revolution for both in- and off-hospital monitoring. Remote biosensing devices can d ...

EPFL2020

Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age

Johan Auwerx, Norman Lionel Moullan

Adipose tissue eosinophils (ATEs) are important in the control of obesity-associated inflammation and metabolic disease. However, the way in which ageing impacts the regulatory role of ATEs remains unknown. Here, we show that ATEs undergo major age-related ...

2020

PREC 2019: Personal Robots for Exercising and Coaching

Ayberk Özgür, Arzu Güneysu Özgür

Exercising is strongly recommended for prevention and treatment of pathologies with high prevalence such as cardiovascular diseases, cancer, and diabetes. The World Health Organization (WHO) states that insufficient physical activity is one of the leading ...

IEEE2019

Ultra high magnetic field for glial contribution into brain metabolism studied by MR spectroscopy and CEST methods for molecular imaging of glycogen

Elise Marie Catherine Vinckenbosch

Magnetic resonance at ultra-high field increases signal and spectral dispersion. In this thesis, I use those characteristics to investigate three different subjects in 13C spectroscopy, hyperpolarized methods and chemical exchange saturation transfer (CEST ...

EPFL2018

Robust ECG Denoising for eHealth Applications

Guglielmo Frigo

Portable monitoring devices have provided an important cost-effective solution in the development of eHealth applications, providing opportunities for population-wide promotion of physical activity. Monitoring heart profile parameters during extensive acti ...

IEEE2018

Nuclear quantum effects enter the mainstream

Michele Ceriotti

Atomistic simulations of chemical, biological and materials systems have become increasingly precise and predictive owing to the development of accurate and efficient techniques that describe the quantum mechanical behaviour of electrons. Nevertheless, the ...

2018

Robust heart rate estimation using wrist-type photoplethysmographic signals during physical exercise: an approach based on adaptive filtering

Jean-Marc Vesin, Sibylle Fallet

Photoplethysmographic (PPG) signals are easily corrupted by motion artifacts when the subjects perform physical exercise. This paper introduces a two-step processing scheme to estimate heart rate (HR) from wrist-type PPG signals strongly corrupted by motio ...

Institute of Physics2017

Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle

Chiara Greggio, Johan Auwerx, Carlos Canto Alvarez, Xu Wang, Pooja Jha

Mitochondrial dysfunction is a hallmark of multiple metabolic complications. Physical activity is known to increase mitochondrial content in skeletal muscle, counteracting age-related decline in muscle function and protecting against metabolic and cardiova ...

Cell Press2017

On the (un) predictability of a large intragenic fitness landscape

Jeffrey David Jensen, Claudia Bank, Sebastian Matuszewski

The study of fitness landscapes, which aims at mapping genotypes to fitness, is receiving ever-increasing attention. Novel experimental approaches combined with next-generation sequencing (NGS) methods enable accurate and extensive studies of the fitness e ...

National Academy of Sciences2016