Publications associées à Syndrome confusionnel (délirium)

Robotically-induced auditory-verbal hallucinations: combining self-monitoring and strong perceptual priors

Olaf Blanke, Fosco Bernasconi, Melissa Faggella, Nathan Quentin Faivre, Pavo Orepic

Background. Inducing hallucinations under controlled experimental conditions in nonhallucinating individuals represents a novel research avenue oriented toward understanding complex hallucinatory phenomena, avoiding confounds observed in patients. Audito ...

2024

Identification of biopsychological trait markers in functional neurological disorders

Serafeim Loukas

Weber et al. provide evidence in support of a stress-diathesis model of functional neurological disorders. They identify trauma history in the form of emotional neglect as a psychological risk factor, and reduced hippocampus and amygdala volume as a predis ...

OXFORD UNIV PRESS2022

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Simone Astori, Marie-Isabelle Guillot de Suduiraut, Ioannis Zalachoras, Mandy Meijer

Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in ...

2022

Mind blanking is a distinct mental state linked to a recurrent brain profile of globally positive connectivity during ongoing mentation

Dimitri Nestor Alice Van De Ville, Sepehr Mortaheb

Mind blanking (MB) is a waking state during which we do not report any mental con-tent. The phenomenology of MB challenges the view of a constantly thinking mind. Here, we comprehensively characterize the MB's neurobehavioral profile with the aim to deline ...

National Academy of Sciences2022

Sensorimotor conflicts induce somatic passivity and louden quiet voices in healthy listeners

Olaf Blanke, Nathan Quentin Faivre, Giulio Rognini, Oliver Alan Kannape, Pavo Orepic

Sensorimotor conflicts are known to alter the perception of accompanying sensory signals, and deficits in sensory attenuation have been observed in schizophrenia. In the auditory domain, self-generated tones or voices (compared to tones or voices presented ...

2021

Structural control energy of resting-state functional brain states reveals less cost-effective brain dynamics in psychosis vulnerability

Dimitri Nestor Alice Van De Ville, Marie Schaer

How the brain's white-matter anatomy constrains brain activity is an open question that might give insights into the mechanisms that underlie mental disorders such as schizophrenia. Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurodevelopmental dis ...

Wiley2021

Topology predicts long-term functional outcome in early psychosis

Kathryn Hess Bellwald, Martina Scolamiero, Kim Do

Early intervention in psychosis is crucial to improving patient response to treatment and the functional deficits that critically affect their long-term quality of life. Stratification tools are needed to personalize functional deficit prevention strategie ...

2021

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

Cristina Ramona Cudalbu, Veronika Rackayová

Type C hepatic encephalopathy (type C HE) is increasingly suspected in children with chronic liver disease (CLD), and believed to underlie long-term neurocognitive difficulties. The molecular underpinnings of type C HE in both adults and children are incom ...

Nature Research2020

Sensorimotor Induction of Auditory Misattribution in Early Psychosis

Olaf Blanke, Alessandra Griffa, Fosco Bernasconi, Andrea Serino, Kim Do, Roy Salomon, Patric Hagmann, Giulio Rognini, Silvia Marchesotti, Pierre Progin

Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hall ...

2020

Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease

Bernard Lanz, Katarzyna Pierzchala, Ileana Ozana Jelescu, Carole Poitry-Yamate, Ting Yin, Yujian Diao

Brain glucose hypometabolism has been singled out as an important contributor and possibly main trigger to Alzheimer's disease (AD). Intracerebroventricular injections of streptozotocin (icv-STZ) cause brain glucose hypometabolism without systemic diabetes ...

2020

Multi-Modal Acute Stress Recognition Using Off-the-Shelf Wearable Devices

David Atienza Alonso, Amir Aminifar, Adriana Arza Valdes, Fabio Isidoro Tiberio Dell'Agnola, Victoriano Montesinos Canovas

Monitoring stress and, in general, emotions has attracted a lot of attention over the past few decades. Stress monitoring has many applications, including high-risk missions and surgical procedures as well as mental/emotional health monitoring. In this pap ...

IEEE2019

A computer vision system for deep learning-based detection of patient mobilization activities in the ICU

Alexandre Massoud Alahi

Early and frequent patient mobilization substantially mitigates risk for post-intensive care syndrome and long-term functional impairment. We developed and tested computer vision algorithms to detect patient mobilization activities occurring in an adult IC ...

Springer2019

RETRACTED: Insular cortex processes aversive somatosensory information and is crucial for threat learning

Ralf Schneggenburger, Olexiy Kochubey, Wei Tang, Michael Kintscher, Denys Osypenko, Shriya Palchaudhuri, Emmanuelle Marie Brigitte Berret

Learning about threats is essential for survival. During threat learning, an innocuous sensory percept such as a tone acquires an emotional meaning when paired with an aversive stimulus such as a mild footshock. The amygdala is critical for threat memory f ...

American Association for the Advancement of Science2019

Electrophysiological correlates of visual backward masking in high schizotypic personality traits participants

Michael Herzog, Christine Mohr, Maya Roinishvili, Ophélie Gladys Favrod, Guillaume Sierro

Visual backward masking is strongly deteriorated in patients with schizophrenia. Masking deficits are associated with strongly reduced amplitudes of the global field power in the EEG. Healthy participants who scored high in cognitive disorganization (a sch ...

Elsevier2017

Neural correlates of visual backward masking in psychosis

Michael Herzog, Ophélie Gladys Favrod, Christine Mohr, Maya Roinishvili, Janir Nuno Ramos Antunes Da Cruz, Albulena Jashari-Shaqiri

In visual backward masking (VBM), a target is followed by a mask, which deteriorates performance on the target. Schizophrenia and first episodes patients show strong behavioral deficits, reflected in strongly reduced amplitudes of the EEG as compared to co ...

2017

In vivo neurochemistry of the ventral striatum and social competition in Homo sapiens

Alina Veronika Irene Strasser

Ventral striatal function and trait anxiety have been shown to influence reward-seeking behaviour and social competition in humans. Moreover, social status perceptions have been shown to modulate ventral striatal function. The neurochemical underpinnings o ...

EPFL2017

Distinct locomotor control and awareness in awake sleepwalkers

Olaf Blanke, Oliver Alan Kannape

Sleepwalkers’ complex nocturnal behaviors have inspired fictional characters from Shakespeare’s Lady Macbeth to Polidori’s Vampyre to Cesare, the homicidal somnambulist in The Cabinet of Dr Caligari. Yet although the underlying pathophysiology of sleepwalk ...

Elsevier2017

Visual backward masking and the schizophrenia spectrum: EEG correlates

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Janir Nuno Ramos Antunes Da Cruz, Albulena Jashari-Shaqiri

Schizophrenia is a heterogeneous disease strongly influenced by genetic factors. We have previously shown that visual backward masking (VBM) is a very sensitive endophenotype of schizophrenia (Chkonia et al., 2010). Importantly, not only patients but also ...

2017

Electrophysiological Correlates of Visual Backward Masking in Schizotypy

Michael Herzog, Christine Mohr, Ophélie Gladys Favrod, Guillaume Sierro

Visual deficits are well documented in schizophrenia. For example, a Vernier is followed by a blank inter-stimulus interval (ISI) and then a grating mask. Observers indicate the direction of the Vernier offset (left vs right). Patients need ISIs that are 1 ...

2016

A Randomized Controlled Trial of the Effectiveness of Computer-Assisted Cognitive Remediation (CACR) in Adolescents with Psychosis or at High Risk of Psychosis

Michael Herzog

Background: Computer assisted cognitive remediation (CACR) was demonstrated to be efficient in improving cognitive deficits in adults with psychosis. However, scarce studies explored the outcome of CACR in adolescents with psychosis or at high risk. Aims: ...

Cambridge University Press2014