Publications associées à Douleur

Who says you are so sick? An investigation on individual susceptibility to cybersickness triggers using EEG, EGG and ECG

In this research paper, we conducted a study to investigate the connection between three objective measures: Electrocardiogram(ECG), Electrogastrogram (EGG), and Electroencephalogram (EEG), and individuals' susceptibility to cybersickness. Our primary obje ...

2024

A Stand-Alone Augmented Reality Intervention for Chronic Pain using Embodied Systolic Stimulation

Sylvain Cardin, Andrea Serino, Robert Leeb, Oliver Alan Kannape, Skander Mensi, Fabien Bourban, Alexis Dorier

Chronic pain presents a tremendous personal, societal, and financial burden. Treatment options are often limited to managing symptoms as opposed to treating the causes, and the consequences of pharmacological treatments can be immensely harmful as evidence ...

IEEE2023

Prefrontal engrams of long-term fear memory perpetuate pain perception

Johannes Gräff, Yechao Han

A painful episode can lead to a life-long increase in an individual's experience of pain. Fearful anticipation of imminent pain could play a role in this phenomenon, but the neurobiological underpinnings are unclear because fear can both suppress and enhan ...

NATURE PORTFOLIO2023

Targeted dorsal root entry zone stimulation alleviates pain due to meralgia paresthetica

Grégoire Courtine, Léonie Asboth, Jocelyne Bloch, Robin Jonathan Demesmaeker, Jimmy James Ravier, Nicolas Hankov, Viviana Aureli, Molywan Vat

Objective. Meralgia paresthetica (MP) is a mononeuropathy of the exclusively sensory lateral femoral cutaneous nerve (LFCN) that is difficult to treat with conservative treatments. Afferents from the LFCN enter the spinal cord through the dorsal root entry ...

IOP Publishing Ltd2022

Tonic pain alters functional connectivity of the descending pain modulatory network involving amygdala, periaqueductal gray, parabrachial nucleus and anterior cingulate cortex

Anne-Christine Schmid

Introduction: Resting state functional connectivity (FC) is widely used to assess functional brain alterations in patients with chronic pain. However, reports of FC accompanying tonic pain in pain-free persons are rare. A network we term the Descending Pai ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Scrambler Therapy for Chronic Pain after Burns and Its Effect on the Cerebral Pain Network: A Prospective, Double-Blinded, Randomized Controlled Trial

Chang-Hyun Park

Chronic pain is common after burn injuries, and post-burn neuropathic pain is the most important complication that is difficult to treat. Scrambler therapy (ST) is a non-invasive modality that uses patient-specific electrocutaneous nerve stimulation and is ...

MDPI2022

Bio-inspired Reflex System for Learning Visual Information for Resilient Robotic Manipulation

Josephine Anna Eleanor Hughes, Kai Christian Junge

Humans have an incredible sense of self-preservation that is both instilled, and also learned through experience. One system which contributes to this is the pain and reflex system which both minimizes damage through involuntary reflex ac- tions and also s ...

2022

An insular cortex - lateral amygdala network in fear learning

Shriya Palchaudhuri

Animals are capable of evaluating sensory cues for possible threats and adapting their behaviours accordingly. Fear learning is an evolutionarily conserved behaviour crucial for animal survival, during which sensory percepts with a negative reinforcing qua ...

EPFL2022

During capsaicin-induced central sensitization, brush allodynia is associated with baseline warmth sensitivity, whereas mechanical hyperalgesia is associated with painful mechanical sensibility, anxiety and somatization

Anne-Christine Schmid

Background Mechanical hyperalgesia and allodynia incidence varies considerably amongst neuropathic pain patients. This study explored whether sensory or psychological factors associate with mechanical hyperalgesia and brush allodynia in a human experimenta ...

WILEY2021

The various forms of sensorimotor plasticity following limb amputation and their link with rehabilitation strategies

Estelle Emeline Raffin

Limb amputation is characterized by complex and intermingled brain reorganization processes combining sensorimotor deprivation induced by the loss of the limb per se, and compensatory behaviors, such as the over-use of the intact or remaining limb. While a ...

2021

Plastic Changes in Pain and Motor Network Induced by Chronic Burn Pain

Chang-Hyun Park

Musculoskeletal diseases with chronic pain are difficult to control because of their association with both central as well as the peripheral nervous system. In burn patients, chronic pain is one of the major complications that cause persistent discomfort. ...

MDPI2021

Overcorrected Implants for Total Shoulder Arthroplasty

Yasmine Boulanaache

Glenohumeral osteoarthritis is a degenerative shoulder joint disease, which causes the breakdown of articular cartilage and bone. People affected by this disease suffer from severe pain and eventually reduced mobility and poor life quality. This disease is ...

EPFL2021

Sensorimotor conflicts induce somatic passivity and louden quiet voices in healthy listeners

Olaf Blanke, Nathan Quentin Faivre, Giulio Rognini, Oliver Alan Kannape, Pavo Orepic

Sensorimotor conflicts are known to alter the perception of accompanying sensory signals, and deficits in sensory attenuation have been observed in schizophrenia. In the auditory domain, self-generated tones or voices (compared to tones or voices presented ...

2021

The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia

Constantin Tuleasca, Anne Donnet

Introduction Gamma Knife radiosurgery (GKR) is a minimally invasive surgical option for drug-resistant essential glossopharyngeal neuralgia (GPN). The authors reviewed pain outcomes and complications in GPN patients who underwent a second or a third GKR fo ...

2020

Enhancing analgesic spinal cord stimulation for chronic pain with personalized immersive virtual reality

Olaf Blanke, Bruno Herbelin, Andrea Serino, Giulio Rognini, Marco Solcà, Robin Mange, Pavo Orepic

Spinal cord stimulation (SCS) is an approved treatment for truncal and limb neuropathic pain. However, pain relief is often suboptimal and SCS efficacy may reduce over time, requiring sometimes the addition of other pain therapies, stimulator revision, or ...

2021

Behavioral and neurophysiological evidence for altered interoceptive bodily processing in chronic pain

Olaf Blanke, Fosco Bernasconi, Hyeongdong Park, Marco Solcà

Whereas impaired multisensory processing of bodily stimuli and distorted body representation are well-established in various chronic pain disorders, such research has focused on exteroceptive bodily cues and neglected bodily signals from the inside of the ...

2020

Shedding light on excessive crying in babies

Dimitri Nestor Alice Van De Ville, François Lazeyras, Lorena Gonçalves de Alcântara e Freitas Krikler

Background Excessive and inconsolable crying behavior in otherwise healthy infants (a condition called infant colic (IC)) is very distressing to parents, may lead to maternal depression, and in extreme cases, may result in shaken baby syndrome. Despite the ...

NATURE PUBLISHING GROUP2021

Cognitive neuroprosthetics for investigating and restoring body perception

Marco Solcà

Our brain constantly receives and integrates a flow of multisensory bodily inputs that are responsible for the way our body is represented and consciously experienced. However, in some pathological conditions, patients might experience altered perceptions ...

EPFL2019

Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Federica Barberi, Dario Bortolotti

Conventional leg prostheses do not convey sensory information about motion or interaction with the ground to aboveknee amputees, thereby reducing confidence and walking speed in the users that is associated with high mental and physical fatigue(1-4). The l ...

2019

RETRACTED: Insular cortex processes aversive somatosensory information and is crucial for threat learning

Ralf Schneggenburger, Olexiy Kochubey, Wei Tang, Michael Kintscher, Denys Osypenko, Shriya Palchaudhuri, Emmanuelle Marie Brigitte Berret

Learning about threats is essential for survival. During threat learning, an innocuous sensory percept such as a tone acquires an emotional meaning when paired with an aversive stimulus such as a mild footshock. The amygdala is critical for threat memory f ...

American Association for the Advancement of Science2019