Publications associées à Chaîne principale

On-Demand Cross-Linkable Bottlebrush Polymers for Voltage- Driven Artificial Muscles

Frank Nüesch, Francis Owusu, Yeerlan Adeli

Dielectric elastomer actuators (DEAs) generate motion resembling natural muscles in reliability, adaptability, elongation, and frequency of operation. They are highly attractive in implantable soft robots or artificial organs. However, many applications of ...

AMER CHEMICAL SOC2023

Identifying the origin of local flexibility in a carbohydrate polymer

Klaus Kern, Stephan Rauschenbach, Sabine Abb

Correlating the structures and properties of a polymer to its monomer sequence is key to understanding how its higher hierarchy structures are formed and how its macroscopic material properties emerge. Carbohydrate polymers, such as cellulose and chitin, a ...

National Academy of Sciences2021

Compound for uses in optical and electrooptical devices

Giuseppe Sforazzini

which can also be embedded into a conjugated oligomeric of polymeric backbone, is proposed for optical and electro optical applications. ...

2017

Synthesis and Characterisation of Semiaromatic Polyamides Comprising Benzofurobenzofuran Repeating Units

Rosario Scopelliti, Farzaneh Fadaei Tirani, Holger Frauenrath, Anne-Clémence Corminboeuf, Daniel Görl, Alberto Fabrizio, Bilal Özen, Thomas Schmaltz, Julien Philippe Cretenoud

Semiaromatic polyamides are attractive engineering polymers owing to their outstanding thermo-mechanical properties. To expand the scope of semiaromatic polyamides by additional optoelectronic features, one may consider the incorporation of extended pi-con ...

2017

High Permittivity Silicones for Dielectric Elastomer Actuators

Simon Johannes Dünki

Many technical advances of modern society sprout from the creation of specially customized polymer materials exhibiting unique combinations of properties uncharted so far. Amid this plurality of highly versatile materials, the class of electroactive polyme ...

EPFL2017

Ionic polymers and use thereof in processing of biomass

Paul Joseph Dyson, Zhaofu Fei, Georgios Savoglidis, Sviatlana Siankevich

The invention provides ionic polymers (IP) consisting of anions and a polymeric backbone containing cations. The invention also provides the ionic polymers incorporated in membranes or attached to solid supports and use of the ionic polymers in processing ...

2017

Surface-Initiated Controlled Radical Polymerization: State-of-the-Art, Opportunities, and Challenges in Surface and Interface Engineering with Polymer Brushes

Harm-Anton Klok, Jian Wang, Piotr Mocny, John Moraes, Justin Orazio Zoppe, Nariye Cavusoglu Ataman

The generation of polymer brushes by surface-initiated controlled radical polymerization (SI-CRP) techniques has become a powerful approach to tailor the chemical and physical properties of interfaces and has given rise to great advances in surface and int ...

2017

Peptide-Polymer Conjugates for Therapeutic Applications

Ana Maria Raduta

Over the last ten years the attention of the pharmaceutical industry has shifted away from small molecules to focus on new biologics such as antibodies, proteins and therapeutic peptides. Herein, peptides have emerged as a particularly interesting category ...

EPFL2015

Catalytic Metal Ions and Enzymatic Processing of DNA and RNA

Matteo Dal Peraro, Andrea Cavalli, Giulia Palermo

Two-metal-ion-dependent nucleases cleave the phosphodiester bonds of nucleic acids via the two-metal-ion (2M) mechanism. Several high-resolution X-ray structures portraying the two-metal-aided catalytic site, together with mutagenesis and kinetics studies, ...

Amer Chemical Soc2015

Cyanine dye polyelectrolytes for organic bilayer solar cells

Roland Hany, Lei Wang, Hui Zhang

Polyelectrolytes composed of an anionic sulfoethyl methacrylate/methacrylate backbone and cationic cyanine dyes counter ions are synthesized. The effective reaction sequence is confirmed by NMR spectroscopy and consists of a thermal radical copolymerizatio ...

Elsevier Sci Ltd2014

Characterization of the Network Structure of PEG Diacrylate Hydrogels Formed in the Presence of N-Vinyl Pyrrolidone

Jeffrey Alan Hubbell, Nicola Tirelli

PEGDA hydrogels copolymerized with NVP using free-radical photopolymerization are used in biomedical applications. These networks consist of a poly(acrylate-co-vinyl pyrrolidone) backbone crosslinked with PEG chains whose crosslink density is dependent on ...

Wiley-V C H Verlag Gmbh2014

TAL Effectors Specificity Stems from Negative Discrimination

Matteo Dal Peraro, Marco Stenta, Basile Isidore Martin Wicky

Transcription Activator-Like (TAL) effectors are DNA-binding proteins secreted by phytopathogenic bacteria that interfere with native cellular functions by binding to plant DNA promoters. The key element of their architecture is a domain of tandem-repeats ...

Public Library of Science2013

Functional, Hyperbranched Polyesters Via Baylis-Hillman Polymerization

Harm-Anton Klok, Sanhao Ji, Frederik Roman Wurm

Hyperbranched polyesters are among the most common hyperbranched polymers. One of the interesting features of hyperbranched polyesters is that they contain unreacted hydroxyl and carboxylic acid groups at the linear and terminal structural units, which can ...

2012

New/Surface-Modified Biocompatible Polymer for ICD Lead Insulation

Rubin Berek Pisarek

The average lifetime of an implanted pacemaker or defibrillator cable (lead) is approximately 10 years. One of the main lead failure mechanisms is deterioration of the insulation, which can be caused by chemical, biological, and mechanical processes. Each ...

EPFL2011

Thermally Induced Cooperative Molecular Reorientation and Nanoscale Polarization Switching Behaviors of Ultrathin Poly(vinylidene fluoride-trifluoroethylene) Films

Nava Setter, Igor Stolichnov, Dong Guo

Ultrathin films of the ferroelectric polymer poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] have recently attracted intensive research interest due to their potential applications in emerging organic devices. As special geometry confinement syst ...

2011

Hybrid Polymer Therapeutics Incorporating Bioresponsive, Coiled Coil Peptide Linkers

Harm-Anton Klok

This article reports the design, synthesis and results of first in vitro model studies of a conceptually novel class of polymer therapeutics in which the cargo is attached to a polymer backbone via a noncovalent, biologically inspired coiled coil linker, w ...

American Chemical Society2010

Hybrid Polymer Therapeutics Incorporating Bioresponsive, Coiled Coil Peptide Linkers

Nanopharmaceuticals or nanomedicines are defined as nanometer sized (1 to 1000 nm) complex systems, consisting of at least two components, one of which being the biologically active moiety such as a drug, peptide, protein or nucleotide. Several nano-sized ...

EPFL2010

X-ray ablation of hyaluronan hydrogels: Fabrication of three-dimensional microchannel networks

Giorgio Margaritondo

We present a simple and highly versatile protocol for polymer ablation: hard x-ray irradiation makes it possible to rapidly depolymerize hyaluronan hydrogels and fabricate three-dimensional network of microchannels. Photodynamic and photochemical analyses ...

American Institute of Physics2009

Degradable Polymer Brushes Prepared via Surface-Initiated Controlled Radical Polymerization

Harm-Anton Klok, Nicolas Bertrand Schüwer, Carl Riachi

Hydrolytically degradable polymer brushes would represent an interesting platform for the development of functional coatings for various biomaterials applications In this manuscript, the surface- initiated atom transfer radical copolymerization of 5.6-benz ...

American Chemical Society2009

Thrombin-sensitive photodynamic agents: A novel strategy for selective synovectomy in rheumatoid arthritis

Hubert van den Bergh

Protease-sensitive macromolecular prodrugs have attracted interest for bio-responsive drug delivery to sites with up-regulated proteolytic activities such as inflammatory or cancerous lesions. Here we report the development of a novel polymeric photosensit ...

2009