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Publications associées (27)

Nanostructured titania coatings for drug-eluting medical implants

Karin Dittmar

Medical implants delivering drugs are used to ensure efficient medication at body sites, at which the conventional administration of drugs is insufficient. The application of drug-delivery coatings is a beneficial concept for implants exposed to mechanical ...

EPFL2009

VR simulation of interventional radiology and microsurgery

Fei Wang

Currently trainees typically learn surgery techniques directly on mocks, animals or cadavers. For safety, cost and ethics reasons, one cannot try all possible strategies to achieve efficient learning. Virtual Reality (VR) based surgery training systems int ...

EPFL2009

Methodologies to assess blood flow in cerebral aneurysms: Current state of research and perspectives

Nikolaos Stergiopoulos, Mohamed Farhat, Philippe Reymond, Luca Augsburger, Edouard Fonck

With intracranial aneurysms disease bringing a weakened arterial wall segment to initiate, grow and potentially rupture an aneurysm, current understanding of vessel wall biology perceives the disease to follow the path of a dynamic evolution and increasing ...

2009

A Real-Time Simulator for Interventional Radiology

Hannes Bleuler, Lindo Robert Duratti, Evren Samur, Fei Wang

Interventional radiologists manipulate guidewires and catheters and steer stents through the patient’s vascular system under X-ray imaging for treatment of vascular diseases. The complexity of these procedures makes trainingmandatory in order to master han ...

2008

Fluid mechanics of cerebral aneurysms and effects of intracranial stents on cerebral aneurysm flow

Luca Augsburger

This thesis focuses on intracranial aneurysms and particularly on the effect of blood flow in the three major phases that characterize an aneurysm: initiation, growth and rupture. As it stands today, blood flow is the major driver of this disease. The unde ...

EPFL2008

Controlled Release Drug Coatings on Flexible Neural Probes

Philippe Renaud, Arnaud Bertsch, André Mercanzini, Jeffrey Alan Hubbell, Philippe Colin, Jean-Charles Bensadoun

We present the development, characterization and in vivo validation of a novel drug eluting coating that has been applied to flexible neural probes. The coating consists of drug eluting nanoparticles loaded with an anti-inflammatory drug embedded in a biod ...

2007

PPS-PEG surface coating to reduce thrombogenicity of small diameter ePTFE vascular grafts

Jeffrey Alan Hubbell

Aims: Patency failure of small vascular synthetic grafts is still a major problem for coronary and peripheral revascularization. Thus, three new surface coatings of small synthetic grafts were tested in an acute pig model to evaluate their thrombogenicity ...

2005

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