Publications de Fabien Patrick Wildhaber

Wearable systems for measuring sweat rate and methods of using the same

Fabien Patrick Wildhaber, Hoël Maxime Guérin, Junrui Zhang

Presented herein are systems and methods for measuring sweat rate of a subject using a wearable system. A sweat rate may be determined automatically based on one or more signals produced by a wetting sensor module in response to a presence of sweat in the ...

2021

Monolithically Integrated Catalyst-Free High Aspect Ratio InAs-on-Insulator (InAsOI) FinFETs for pH Sensing

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Maneesha Rupakula, Junrui Zhang, Francesco Bellando, Clarissa Convertino

In this work, we report a novel Indium Arsenide-on-insulator (InAsOI) FinFET platform designed with record high aspect ratio that favors the use of the devices as charge sensors. InAs has very high mobility among III-V semiconductors and an intrinsic surfa ...

2020

Monolithically integrated catalyst-free High Aspect Ratio InAs-On-Insulator (InAsOI) FinFETs for pH sensing

Mihai Adrian Ionescu, Kirsten Emilie Moselund, Fabien Patrick Wildhaber, Maneesha Rupakula, Junrui Zhang, Francesco Bellando, Clarissa Convertino

In this work, we report a novel Indium Arsenide-on-insulator (InAsOI) FinFET platform designed with record high aspect ratio that favor the use of the devices as charge sensors. InAs has very high mobility among III-V semiconductors and an intrinsic surfac ...

IEEE2019

Apparatus for non-invasive sensing of biomarkers in human sweat

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Erick Antonio Garcia Cordero, Francesco Bellando

Presented herein are devices for collecting and/or channeling a biofluid (e.g., sweat, tears, saliva) and detecting and/or quantifying one or more biomarkers in the biofluid. The biomarker(s) may include, for example, ions, salts thereof, hormones and/or s ...

2019

Sweat Biomarker Sensor Incorporating Picowatt, Three-Dimensional Extended Metal Gate Ion Sensitive Field Effect Transistors

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Hoël Maxime Guérin, Maneesha Rupakula, Erick Antonio Garcia Cordero, Junrui Zhang, Francesco Bellando, Guillaume Charles Henri Herment

Ion sensitive field effect transistors (ISFETs) form a very attractive solution for wearable sensors due to their capacity for ultra-miniaturization, low power operation, and very high sensitivity, supported by complementary metal oxide semiconductor (CMOS ...

2019

CMOS 3D-Extended Metal Gate ISFETs with Near Nernstian Ion Sensitivity

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Maneesha Rupakula, Erick Antonio Garcia Cordero, Junrui Zhang, Francesco Bellando, Neil Ebejer

IEEE2018

Three-Dimensional Integrated Ultra-Low-Volume Passive Microfluidics with Ion-Sensitive Field-Effect Transistors for Multiparameter Wearable Sweat Analyzers

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Erick Antonio Garcia Cordero, Junrui Zhang, Francesco Bellando

Wearable systems could offer noninvasive and real-time solutions for monitoring of biomarkers in human sweat as an alternative to blood testing. Recent studies have demonstrated that the concentration of certain biomarkers in sweat can be directly correlat ...

2018

Embedded Passive Nano-Liter Micropump For Sweat Collection And Analysis

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Montserrat Fernandez-Bolanos Badia, Johan Frédéric Longo, Hoël Maxime Guérin, Erick Antonio Garcia Cordero, Francesco Bellando

This paper presents a method to integrate biocompatible passive microfluidic systems within a sensing platform to allow continuous analysis of sweat in a wearable microsystem. The technology is promising for miniaturization of systems to enable access to b ...

IEEE2018

All CMOS Integrated 3D-Extended Metal Gate ISFETs for pH and Multi-Ion (Na+, K+, Ca2+) sensing

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Maneesha Rupakula, Erick Antonio Garcia Cordero, Junrui Zhang, Francesco Bellando, Guillaume Charles Henri Herment

This paper reports for the first time, smart 3D-Extended-Metal-Gate Ion-Sensitive-Field-Effect-Transistors (3D-EMG-ISFETs), with unique figures of merit: (i) extremely-low-power (down to a record value of 2 pW per sensor under excellent linearity), (ii) al ...

IEEE2018

Lab on skin™: 3D monolithically integrated zero-energy micro/nanofludics and FD SOI ion sensitive FETs for wearable multi-sensing sweat applications

Mihai Adrian Ionescu, Fabien Patrick Wildhaber, Johan Frédéric Longo, Hoël Maxime Guérin, Erick Antonio Garcia Cordero, Francesco Bellando

This paper reports a novel fully integrated low power multi-sensing smart system, which, by wafer-level 3D heterogeneous integration of Ion Sensitive Fully Depleted (FD) FETs and SU-8 micro/nanofludics, achieves the first of its kind wearable multi-sensing ...

2017

Soft nanofluidics governing minority ion exclusion in charged hydrogels

Fabien Patrick Wildhaber, Thomas Michael Braschler, Songmei Wu, Sidi Ahmed Bencherif

We investigate ionic partition of negatively charged molecular probes into also negatively charged, covalently crosslinked alginate hydrogels. The aim is to delimit the domain of validity of the major nanoelectrostatic models, and in particular to assess t ...

Royal Society of Chemistry2015

Ionic and molecular transport through active nanoporous membranes

Fabien Patrick Wildhaber

EPFL2014

Al2O3/W hetero-structured nanopore membranes: From native to tunable nanofluidic diodes

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Songmei Wu

We present here Al2O3/W hetero-structured nanopore membranes which function as native and electrical field tunable nanofluidic diodes. A typical membrane is 100×100 μm2 in size with pore density of ∼ 20/μm2. The nanopores are 26 nm in diameter and 400 nm i ...

IEEE2013

Field effect modulated nanofluidic diode membrane based on Al2O3/W heterogeneous nanopore arrays

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Songmei Wu

We developed Al2O3/W heterogeneous nanopore arrays for field effect modulated nanofluidic diodes. They are fabricated by transferring self-organized nanopores of anodic aluminium oxide into a W thin film. The nanopores are ∼20 nm in diameter and 400 nm in ...

American Institute of Physics2013

Facile fabrication of nanofluidic diode membranes using anodic aluminium oxide

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Oscar Vazquez Mena, Songmei Wu

Active control of ion transport plays important roles in chemical and biological analytical processes. Nanofluidic systems hold the promise for such control through electrostatic interaction between ions and channel surfaces. Most existing experiments rely ...

Royal Soc Chemistry2012

Nanofluidic platform for label-free proteins detection

Philippe Renaud, Nicolas Durand, Fabien Patrick Wildhaber

2009