Publications de Ulrike Lehmann

Highly sensitive SnO2 sensor via reactive laser-induced transfer

Alexander Wokaun, Ulrike Lehmann, Alain Grisel

Gas sensors based on tin oxide (SnO2) and palladium doped SnO2 (Pd:SnO2) active materials are fabricated by a laser printing method, i.e. reactive laser-induced forward transfer (rLIFT). Thin films from tin based metal-complex precursors are prepared by sp ...

Nature Research2016

Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix

Martinus Gijs, Caroline Vandevyver, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

We present a monolithic silicon chip comprising a matrix of 84 single photon avalanche diodes (SPADs) to detect and discriminate fluorescent beads or fluorescently labeled single cells in a polydimethyl(-siloxane) (PDMS) cartridge that is positioned on top ...

Elsevier2012

Microfluidic applications of magnetic particles for biological analysis and catalysis

Martinus Gijs, Frédéric Lacharme, Ulrike Lehmann

American Chemical Society2010

Monolithic Silicon Chip for Immunofluorescence Detection on Single Magnetic Beads

Martinus Gijs, Caroline Vandevyver, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

While fluorescence detection is widely used for bioassays owing to its high sensitivity, a complete fluorescent microscopy setup, comprised of a light source, optical filters, a microscope body, and a camera, still is bulky equipment, compromising its use ...

2010

Manipulation of magnetic microparticles in liquid phases for on-chip biomedical analysis methods

Ulrike Lehmann

Magnetic microparticles and their application in bioanalytical microfluidic systems have been steadily gaining interest in recent years. This progress is fueled by the comparatively large and long range magnetic forces that can be obtained independently of ...

EPFL2008

Microparticle photometry in a CMOS microsystem combining magnetic actuation and in-situ optical detection

Martinus Gijs, Cristiano Niclass, Edoardo Charbon, Ulrike Lehmann, Emile Dupont, Stefano Pietrocola

We present a hybrid CMOS-based microfluidic system that combines magnetic actuation of microparticles with in situ optical detection using single photon avalanche diodes (SPADs). The decoupling of the principles used for actuation and sensing permits a hig ...

2008

On-Chip Sandwich Immunoassay in an Integrated Magneto-Optical CMOS Microsystem

Martinus Gijs, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

We report on an innovative approach to on-chip detection of single fluorescently-labeled magnetic micro-particles by means of Single Photon Avalanche Diode (SPAD) arrays. Our system enables particle separation through magnetic actuation and highly sensitiv ...

2008

On-chip detection of sandwich immunoassay in an integrated magneto-optical CMOS microsystem

Martinus Gijs, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

2008

Particle-Shadow Tracking – Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Martinus Gijs, Cristiano Niclass, Edoardo Charbon, Ulrike Lehmann, Stefano Pietrocola

We present a hybrid CMOS based microsystem where magnetic actuation of microparticles is combined with integrated optical detection via Single Photon Avalanche Diodes (SPADs). The system’s configuration permits the manipulation and detection of single magn ...

2007

Detection of fluorescently labelled magnetic particles for lab-on-a-chip applications

Martinus Gijs, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

2007

Two-Dimensional Magnetic Droplet Manipulation Platform for Miniaturized Bioanalytical Applications

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Ulrike Lehmann

We present a new approach for the manipulation of small liquid samples for the miniaturization of bioanalytical systems. In our system, minute liquid volumes are manipulated via the interaction of a changeable magnetic field and magnetic microparticles con ...

2007

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

Martinus Gijs, Caroline Vandevyver, Virendra Kumar Parashar, Damien de Courten, Ulrike Lehmann

Miniaturized system for bioanalysis have been constantly gaining importance and interest within the recent years. The reduction of sample consumption and reaction time are some of the major advantages of such lab-on-a-chip applications. One of the greatest ...

2007

Detection of Fluorescently Labelled Magnetic Particles for Lab-on-a-chip Applications

Martinus Gijs, Edoardo Charbon, Ulrike Lehmann, Emile Dupont

2007

A CMOS Microsystem Combining Magnetic Actuation and In-Situ Optical Detection of Microparticles

Martinus Gijs, Cristiano Niclass, Edoardo Charbon, Ulrike Lehmann, Stefano Pietrocola

We present a CMOS-based hybrid microfluidic system that combines the manipulation of magnetic microparticles through a magnetic field with in situ optical detection via single photon avalanche diodes (SPADs). Magnetic particles are actuated within a glass ...

2007

Particle Shadow Tracking - Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Martinus Gijs, Cristiano Niclass, Edoardo Charbon, Ulrike Lehmann, Stefano Pietrocola

We present a hybrid CMOS based microsystem where magnetic actuation of microparticles is combined with integrated optical detection via Single Photon Avalanche Diodes (SPADs). The system’s configuration permits the manipulation and detection of single magn ...

2007

Ulrike Lehmann

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Highly sensitive SnO2 sensor via reactive laser-induced transfer

Fluorescent magnetic bead and cell differentiation/counting using a CMOS SPAD matrix

Microfluidic applications of magnetic particles for biological analysis and catalysis

Monolithic Silicon Chip for Immunofluorescence Detection on Single Magnetic Beads

Manipulation of magnetic microparticles in liquid phases for on-chip biomedical analysis methods

Microparticle photometry in a CMOS microsystem combining magnetic actuation and in-situ optical detection

On-Chip Sandwich Immunoassay in an Integrated Magneto-Optical CMOS Microsystem

On-chip detection of sandwich immunoassay in an integrated magneto-optical CMOS microsystem

Particle-Shadow Tracking – Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Detection of fluorescently labelled magnetic particles for lab-on-a-chip applications

Two-Dimensional Magnetic Droplet Manipulation Platform for Miniaturized Bioanalytical Applications

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

Detection of Fluorescently Labelled Magnetic Particles for Lab-on-a-chip Applications

A CMOS Microsystem Combining Magnetic Actuation and In-Situ Optical Detection of Microparticles

Particle Shadow Tracking - Combining Magnetic Particle Manipulation with In-Situ Optical Detection in a CMOS Microsystem

Magnetic particles as mobile substrates on biochips

A magnetic droplet-based Lab-on-a-Chip

A Lab-on-a-Chip using magnetic droplets

Microfluidic system for analytical applications : a magnetic droplet-based Lab-on-a-Chip

DNA capture and elution in a magnetic droplet manipulation system