Publications de Cristina Martin Olmos

Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation

Cristina Martin Olmos, Anders Meibom, Stéphane Laurent Escrig, Priya Ramakrishna

Increasing soil salinity causes significant crop losses globally; therefore, understanding plant responses to salt (sodium) stress is of high importance. Plants avoid sodium toxicity through subcellular compartmentation by intricate processes involving a h ...

NATURE PORTFOLIO2025

Enzymatic absorption promoters for non-invasive peptide delivery

Cristina Martin Olmos, Angela Steinauer

Peptide drugs offer considerable potential for treating a diverse range of diseases. Yet, their clinical application is generally restricted to injectable therapies. The main challenge hindering their broader use through globally accessible, patient-friend ...

2025

Fossil biocalcite remains open to isotopic exchange with seawater for tens of millions of years

Cristina Martin Olmos, Anders Meibom, Stéphane Laurent Escrig, Jaroslaw Hubert Stolarski, Arthur Adams, Deyanira Graciela Cisneros Lazaro

Fossilized remains of marine calcifiers constitute the physical basis for reconstructions of both deep ocean and sea-surface temperatures going back millions of years, but paleoclimate records derived from their isotope and trace-element chemistry can be b ...

Springer Nature2024

Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis

Cristina Martin Olmos, Anders Meibom, Stéphane Laurent Escrig, Gaëlle Delphine Toullec, Nils Rädecker, Claudia Isabella Pogoreutz, Guilhem Maurice Louis Banc-Prandi

Background
Global warming is causing large-scale disruption of cnidarian-Symbiodiniaceae symbioses fundamental to major marine ecosystems, such as coral reefs. However, the mechanisms by which heat stress perturbs these symbiotic partnership ...

Springer Science and Business Media LLC2024

Symbiotic nutrient exchange enhances the long-term survival of cassiosomes, the autonomous stinging-cell structures of Cassiopea

Cristina Martin Olmos, Anders Meibom, Niclas Heidelberg Lyndby, Gaëlle Delphine Toullec, Nils Rädecker, Claudia Isabella Pogoreutz, Guilhem Maurice Louis Banc-Prandi

Medusae of the widely distributed upside-down jellyfish Cassiopea release autonomous, mobile stinging structures. These so-called cassiosomes play a role in predator defense and prey capture, and are major contributors to “contactless” stinging incidents i ...

2023

Data for "Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis"

Cristina Martin Olmos, Anders Meibom, Stéphane Laurent Escrig, Gaëlle Delphine Toullec, Nils Rädecker, Claudia Isabella Pogoreutz, Guilhem Maurice Louis Banc-Prandi

Raw data associated with the publication "Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis". Temperature profile, daily measurements, physiological measurements, element ...

Zenodo2023

Correlated cryo-SEM and CryoNanoSIMS imaging of biological tissue

Arnaud Comment, Cristina Martin Olmos, Tian Cheng, Anders Meibom, Stéphane Laurent Escrig, Florent Olivier Vivien Plane, Louise Helene Soegaard Jensen, Nils Rädecker

BackgroundThe development of nanoscale secondary ion mass spectrometry (NanoSIMS) has revolutionized the study of biological tissues by enabling, e.g., the visualization and quantification of metabolic processes at subcellular length scales. However, the a ...

2023

Nanoliter Liquid Packaging in a Bioresorbable Microsystem by Additive Manufacturing and its Application as a Controlled Drug Delivery Device

Arnaud Bertsch, Jürgen Brugger, Cristina Martin Olmos, Jongeon Park

Precise packaging of nanoliter amounts of liquid in a microsystem is important for many biomedical applications. However, existing liquid encapsulation technologies have limitations in terms of liquid waste, evaporation, trapped bubbles, and liquid degrada ...

2023

Integrating environmental variability to broaden the research on coral responses to future ocean conditions

Cristina Martin Olmos, Nils Rädecker

Our understanding of the response of reef-building corals to changes in their physical environment is largely based on laboratory experiments, analysis of long-term field data, and model projections. Experimental data provide unique insights into how organ ...

2021

Integrated elastomer-based device for measuring the mechanics of adherent cell monolayers

Herbert Shea, Alexandre Poulin, Cristina Martin Olmos, Francesca Sorba

Cells in the body collectively sustain mechanical deformations in almost all physiological functions. From the morphogenesis stage, cells' ability to sustain stress is essential for the body's well-being. Several pathologies have been associated with abnor ...

2019

An ultra-fast mechanically active cell culture substrate

Samuel Rosset, Herbert Shea, Alexandre Poulin, Cristina Martin Olmos, Francesca Sorba, Matthias Imboden

We present a mechanically active cell culture substrate that produces complex strain patterns and generates extremely high strain rates. The transparent miniaturized cell stretcher is compatible with live cell microscopy and provides a very compact and por ...

Nature Research2018

Optimization of thin-film highly-compliant elastomer sensors for contractility measurement of muscle cells

Samuel Rosset, Mélanie Favre, Herbert Shea, Alexandre Poulin, Cristina Martin Olmos, Oluwaseun Adelowo Araromi, Francesca Sorba, Matthias Imboden

Test assays capable of providing quantitative characterization of the contraction of cardiac and smooth muscle cells are of great need for drug development and screening. Several methodologies have been proposed for achieving measurement of cell contractil ...

Elsevier Science Bv2016

Simple and easily controllable parabolic-shaped microlenses printed on polymeric mesas

Jürgen Brugger, Joo Yeon Kim, Cristina Martin Olmos

A simple and easy shape-controllable approach is demonstrated for the fabrication of parabolic-shaped polymer microlenses (mu-lenses), which are widely used in bio-imaging systems such as microfluidic and lab-on-a-chip systems for improving the image quali ...

Royal Society of Chemistry2013

Fluid-mediated parallel self-assembly of polymeric micro-capsules for liquid encapsulation and release

Alcherio Martinoli, Jürgen Brugger, Grégory Mermoud, Loïc Jacot-Descombes, Luis Guillermo Villanueva Torrijo, Cristina Martin Olmos, Victor Javier Cadarso Busto, Rosario Maurizio Gullo, Massimo Mastrangeli

Fluid-mediated self-assembly is one of the most promising routes for assembling and packaging smart microsystems in a scalable and cost-efficient way. In this work the pairwise fluidic self-assembly of 100 μm-sized SU-8 cylinders is studied with respect to ...

2013

Resistless Fabrication of Nanoimprint Lithography (NIL) Stamps Using Nano-Stencil Lithography

Jürgen Brugger, Oscar Vazquez Mena, Katrin Sidler Arnet, Andreea Veronica Savu, Luis Guillermo Villanueva Torrijo, Cristina Martin Olmos

In order to keep up with the advances in nano-fabrication, alternative, cost-efficient lithography techniques need to be implemented. Two of the most promising are nanoimprint lithography (NIL) and stencil lithography. We explore here the possibility of fa ...

MDPI2013

All-stencil transistor fabrication on 3D silicon substrates

Philippe Langlet, Cyrille Hibert, Peter Vettiger, Jürgen Brugger, Oscar Vazquez Mena, Katrin Sidler Arnet, Andreea Veronica Savu, Luis Guillermo Villanueva Torrijo, Cristina Martin Olmos

The standard lithographic techniques to fabricate electronic components involve the use of polymers, baking steps and chemicals. This typically restricts their application to flat substrates made up of standard materials. Stencil lithography has been propo ...

Iop Publishing Ltd2012

Containers assembled in fluid and corresponding production

Alcherio Martinoli, Jürgen Brugger, Grégory Mermoud, Cristina Martin Olmos

A method for fabricating a fluid container, wherein at least two half containers are mated in said fluid to be contained in said container. This method allows the incorporation of prefabricated devices into each half containers as well as the functional co ...

2011

Localized Ion Implantation Through Micro/Nanostencil Masks

Philippe Langlet, Jürgen Brugger, Oscar Vazquez Mena, Luis Guillermo Villanueva Torrijo, Cristina Martin Olmos

A method is presented that allows the deﬁnition of micrometer- and submicrometer-sized implanted structures in silicon without using photoresist patterning. The process is based on the use of stencils as masks in a conventional ion implanter, and is tested ...

Institute of Electrical and Electronics Engineers2011

Stress and aging minimization in photoplastic AFM probes

Jürgen Brugger, Luis Guillermo Villanueva Torrijo, Cristina Martin Olmos

Photostructurable epoxy based resists, like SU-8, are soft materials with a Young’s Modulus around 4 GPa, which makes them particularly suitable as base material to fabricate Atomic Force Microscopy (AFM) probes for non-destructive analysis of fragile samp ...

Elsevier2009

Magnetic Nanocrystals Modified Epoxy Photoresist for fabrication of NEMS and MEMS

Jürgen Brugger, Cristina Martin Olmos

2008