Liang Qiao

Cette personne n’est plus à l’EPFL

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Publications associées (47)

Plate for matrix-assisted laser desorption ionization mass spectrometry, comprises electroconductive substrate covered with sintered nanoparticles, deposited as array of spots, for supporting ionization of sorbed sample molecules

Hubert Girault, Michel Prudent, Niels Erik Lion, Christophe Roussel, Jingjing Wan, Liang Qiao

NOVELTY - A plate comprises an electroconductive substrate (1) at least partially covered with sintered nanoparticles (2), deposited as an array of individual spots, for use as a sorbing phase for a sample, and for supporting ionization of sorbed sample mo ...

2009

Photocatalytic Redox Reactions for In-Source Peptide Fragmentation

Hubert Girault, Hongyan Bi, Jérôme Waser, Liang Qiao

In-source photocatalytic redox reactions based on a photosensitive target plate have been developed to realize peptide fragmentation during laser desorption ionization. Sample peptides and glucose are simply deposited on a spot of sintered TiO2 nanoparticl ...

2009

Kinetics of Proteolytic Reactions in Nanoporous Materials

Hubert Girault, Hongyan Bi, Liang Qiao

Proteolysis with proteases preloaded within nanopores of porous material is a very fast process, where proteins can be digested in minutes compared to the conventional bulk enzyme reactions taking place over hours. To model this surprising phenomenon, a mo ...

American Chemical Society2009

TiO2 Printed Aluminum Foil: Single-Use Film for a Laser Desorption/Ionization Target Plate

Valérie Devaud, Hubert Girault, Hongyan Bi, Liang Qiao

Single-use aluminum foil-based laser desorption/ionization (LDI) target plates have been developed for mass spectrometry (MS) analysis and provide detection results comparable to those of commercial stainless steel plates while offering a convenient way to ...

2009

Plate for matrix-assisted laser desorption ionization mass spectrometry for, e.g. analyzing peptide, has substrate that is covered with light sensitive matrix with light absorber, charge carrier, probe molecule and photo-sensitizer

Hubert Girault, Niels Erik Lion, Christophe Roussel, Liang Qiao

NOVELTY - The plate has electrically conductive substrate (1) that is covered with light sensitive matrix (2). The matrix comprises light absorber, charge carrier, probe molecule and photo-sensitizer (3) arranged to oxidize probe molecule by irradiation of ...

2008

In-source photocatalytic reduction of disulfide bonds during laser desorption ionization

Hubert Girault, Hongyan Bi, Liang Qiao

A photosensitive plate based on sintered TiO2 nanoparticles has been developed to carry out in-source photo-induced reductions for cleavage of disulfide bridges using glucose as a hole scavenger during laser desorption ionization. ...

2008

Specific On-Plate Enrichment of Phosphorylated Peptides for Direct MALDI-TOF MS Analysis

Hubert Girault, Christophe Roussel, Jingjing Wan, Liang Qiao

An on-plate specific enrichment method is presented for the direct analysis of peptides phosphorylation. An array of sintered TiO2 nanoparticle spots was prepared on a stainless steel plate to provide porous substrate with a very large specific surface and ...

American Chemical Society2007

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