Publications de Georg Fantner | EPFL Graph Search

Fabrication of fluid-compatible trilayer cantilevers with integrated piezoelectric actuators

Luis Guillermo Villanueva Torrijo, Georg Fantner, Matthias Neuenschwander, Damien Maillard, Nahid Hosseini, Mustafa Kangül

Microcantilevers are popular transducers thanks to their simple design and a high sensitivity. In many applications, the cantilevers need to be actuated, either to induce a controlled deflection or to excite the resonance. This can be achieved with integra ...

2025

Data-driven control in atomic force microscopy using a genetic algorithm

Alireza Karimi, Georg Fantner

Increasing the scanning speed in Atomic Force Microscopy (AFM) relies on improving the tracking performance in the vertical direction of motion. The lightly damped resonances of piezo-actuators utilized in AFM nano-positioning stages hinder the maximum ach ...

2025

Controlled Sensing of User-Defined Aptamer-Based Targets Using Scanning Ionic Conductance Spectroscopy

Aleksandra Radenovic, Lely Feletti, Georg Fantner, Barney Frederick Drake, Marcos Penedo Garcia, Helena Miljkovic, Wayne Yang Wen Wei, Zahra Ayar Dulabi

Solid-state nanopores offer the possibility of detecting disease biomarkers in early diagnostic applications. Standard approaches harness fingerprinting, where protein targets are bound to DNA carriers and detected in free translocation with a solid-state ...

2025

Interface flexibility controls the nucleation and growth of supramolecular networks

Georg Fantner, Maartje Martina Cornelia Bastings, Cem Tekin, Vincenzo Caroprese, Navid Asmari Saadabad, Veronika Cencen

Supramolecular networks are abundantly present in nature and, like crystalline materials, often develop from an initial nucleation site, followed by growth based on directional interactions between components. Traditionally, the binding strength and direct ...

2025

Deep learning for enhancement of low-resolution and noisy scanning probe microscopy images

Georg Fantner, Marcos Penedo Garcia

In this study, we employed traditional methods and deep learning models to improve resolution and quality of low-resolution AFM images made under standard ambient scanning. Both traditional methods and deep learning models were benchmarked and quantified r ...

Beilstein Institut2025

Lattice bond chains administer kink anisotropy and inform strategies of theophylline crystal self-healing

Georg Fantner

How molecular-level understanding of the crystal growth mechanisms and their relation to lattice bonds informs the rational design of crystals with desired shapes and properties has remained elusive. Here we employ theophylline crystals and drive them into ...

2025

A hermetically closed sample chamber enables time-lapse nano-characterization of pathogenic microorganisms in vitro

John McKinney, Santiago Harald Andany, Georg Fantner, Navid Asmari Saadabad

Pathogenic microorganisms, such as pathogenic mycobacteria, pose a global health burden. Studying these organisms is crucial for gaining detailed knowledge about the pathogens and the diseases they cause. To handle pathogenic organisms, specific biosafety ...

ROYAL SOC CHEMISTRY2025

Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism

Georg Fantner, Navid Asmari Saadabad, Marcos Penedo Garcia

Hundreds of thousands die annually from malaria caused by Plasmodium falciparum (Pf), with the emergence of drug-resistant parasites hindering eradication efforts. Antimicrobial peptides (AMPs) are known for their ability to disrupt pathogen membranes with ...

2025

Enhanced feedback performance in off-resonance AFM modes through pulse train sampling

Santiago Harald Andany, Georg Fantner, Mustafa Kangül, Navid Asmari Saadabad, Marcos Penedo Garcia

Dynamic atomic force microscopy (AFM) modes that operate at frequencies far away from the resonance frequency of the cantilever (off-resonance tapping (ORT) modes) can provide high-resolution imaging of a wide range of sample types, including biological sa ...

Beilstein-Institut2024

Open-source microscope add-on for structured illumination microscopy

Matthias Lütolf, Theo Lasser, Aleksandra Radenovic, John McKinney, Georg Fantner, Olivier François Venzin, Mélanie Thérèse Marie Hannebelle, Tomas Lukes, Samuel Mendes Leitão, Antonius Chrisnandy, Chiara Toniolo, Andrew Charles Oates, Prabhu Prasad Swain, Nathan Cyprien Arsène Ronceray

Super-resolution techniques expand the abilities of researchers who have the knowledge and resources to either build or purchase a system. This excludes the part of the research community without these capabilities. Here we introduce the openSIM add-on to ...

Nature Portfolio2024

Mechanical morphotype switching as an adaptive response in mycobacteria

John McKinney, Georg Fantner, Chiara Toniolo

Invading microbes face a myriad of cidal mechanisms of phagocytes that inflict physical damage to microbial structures. How intracellular bacterial pathogens adapt to these stresses is not fully understood. Here, we report the discovery of a virulence mech ...

Amer Assoc Advancement Science2024

Deterministic grayscale nanotopography to engineer mobilities in strained MoS2 FETs

Giovanni Boero, Andras Kis, Jürgen Brugger, Georg Fantner, Nicola Marzari, Norma Rivano, Zhenyu Wang, Xia Liu, Ana Conde Rubio, Berke Erbas, Mitali Banerjee, Jin Jiang, Marcos Penedo Garcia

Field-effect transistors (FETs) based on two-dimensional materials (2DMs) with atomically thin channels have emerged as a promising platform for beyond-silicon electronics. However, low carrier mobility in 2DM transistors driven by phonon scattering remain ...

Nature Research2024

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

Santiago Harald Andany, Georg Fantner, Bahareh Ghadiani, Mustafa Kangül, Maartje Martina Cornelia Bastings, Cem Tekin, Veronika Cencen, Marcos Penedo Garcia

High-speed atomic force microscopy (HS-AFM) is a popular molecular imaging technique for visualizing single-molecule biological processes in real-time due to its ability to image under physiological conditions in liquid environments. The photothermal off-r ...

Journal Of Visualized Experiments2024

A polymer-semiconductor-ceramic cantilever for high-sensitivity fluidcompatible microelectromechanical systems

Oliver Peric, Santiago Harald Andany, Georg Fantner, Dirk Grundler, Matthias Neuenschwander, Nahid Hosseini, Marcos Penedo Garcia

Active microelectromechanical systems (MEMS) with integrated electronic sensing and actuation can provide fast and sensitive measurements of force, acceleration and biological analytes. Strain sensors integrated onto MEMS cantilevers are widely used to tra ...

Springer Science and Business Media LLC2024

Combining thermal scanning probe lithography and dry etching for grayscale nanopattern amplification

Giovanni Boero, Arnaud Bertsch, Andras Kis, Jürgen Brugger, Georg Fantner, Zhenyu Wang, Xia Liu, Ana Conde Rubio, Berke Erbas, Mitali Banerjee, Marcos Penedo Garcia

Grayscale structured surfaces with nanometer-scale features are used in a growing number of applications in optics and fluidics. Thermal scanning probe lithography achieves a lateral resolution below 10 nm and a vertical resolution below 1 nm, but its maxi ...

Springernature2024

Nanopore-based scanning system and method

Aleksandra Radenovic, Georg Fantner, Samuel Mendes Leitão, Vytautas Navikas

Nanopore-based scanning system including a probe structure comprising a nanopore; suction means configured to draw an end of a (bio)molecule inside the nanopore and inside the probe structure, single or multiple times; and displacement means configured to ...

2023

A high-bandwidth voltage amplifier for driving piezoelectric actuators in high-speed atomic force microscopy

Santiago Harald Andany, Georg Fantner, Adrian Pascal Nievergelt, Mustafa Kangül

High-speed atomic force microscopy (HS-AFM) is a technique capable of revealing the dynamics of biomolecules and living organisms at the nanoscale with a remarkable temporal resolution. The phase delay in the feedback loop dictates the achievable speed of ...

AIP Publishing2023

Label-Free Long-Term Methods for Live Cell Imaging of Neurons: New Opportunities

Georg Fantner, Samuel Mendes Leitão, Zahra Ayar Dulabi

Time-lapse light microscopy combined with in vitro neuronal cultures has provided a significant contribution to the field of Developmental Neuroscience. The establishment of the neuronal polarity, i.e., formation of axons and dendrites, key structures resp ...

MDPI2023

Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds

Aleksandra Radenovic, Georg Fantner, Samuel Mendes Leitão, Barney Frederick Drake, Sanjin Marion, Vytautas Navikas, Simon Finn Mayer, Helena Miljkovic

In current nanopore-based label-free single-molecule sensing technologies, stochastic processes influence the selection of translocating molecule, translocation rate and translocation velocity. As a result, single-molecule translocations are challenging to ...

2023

Engineering Optically Active Defects in Hexagonal Boron Nitride Using Focused Ion Beam and Water

Andras Kis, Aleksandra Radenovic, Georg Fantner, Evgenii Glushkov, Ahmet Avsar, Michal Daniel Macha, Vytautas Navikas, Aqeel Ahmed, Cheol Yeon Cheon, Nathan Cyprien Arsène Ronceray

Hexagonal boron nitride (hBN) has emerged as a promising material platform for nanophotonics and quantum sensing, hosting optically active defects with exceptional properties such as high brightness and large spectral tuning. However, precise control over ...

AMER CHEMICAL SOC2022