Publications de Elena Bianchi | EPFL Graph Search

Label-free identification of activated T lymphocytes through tridimensional microsensors on chip

Carlotta Guiducci, Elena Bianchi, Enrica Rollo, George Coukos, Enrico Tenaglia, Alexandre Harari

Label-free approaches to assess cell properties ideally suit the requirements of cell-based therapeutics, since they permit to characterize cells with minimal perturbation and manipulation, at the benefit of sample recovery and re-employment for treatment. ...

Elsevier2017

Fabrication of Biocompatible Monolithic Microchannels with High Pressure-Resistance Using Direct Polymerization of PEG-Modified PMMA

Martinus Gijs, Ata Tuna Ciftlik, Elena Bianchi

Withstanding high pressures in polymeric microchannels is an important requirement for many biological applications. Here, a simple direct polymerization through a polyester photomask is applied to obtain monolithic polyethylene glycol (PEG)-modified poly( ...

Wiley-Blackwell2014

Metal-coated silicon micropillars for freestanding 3D-electrode arrays in microchannels

Samuel Kilchenmann, Carlotta Guiducci, Elena Bianchi, Enrica Rollo

This paper presents a fabrication process for arrays of high-aspect-ratio micropillar electrodes, which are freestanding 3D structures that feature metal sidewalls connected to passivated planar wires. Facing vertical electrodes are considered to be a key ...

Elsevier2013

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays

Elena Bianchi

Recruitment of leukocytes from blood to tissues is a multi-step process playing a major role in the activation of inflammatory responses. Tethering and rolling of leukocytes along the vessel wall, followed by arrest and transmigration through the endotheli ...

Elsevier2013

Detecting particles flowing through interdigitated 3D microelectrodes

Samuel Kilchenmann, Enrico Accastelli, Carlotta Guiducci, Elena Bianchi, Enrica Rollo

Counting cells in a large microchannel remains challenging and is particularly critical for in vitro assays, such as cell adhesion assays. This paper addresses this issue, by presenting the development of interdigitated three-dimensional electrodes, which ...

Ieee2012

Integrating Bio-sensing Functions on CMOS Chips

Yusuf Leblebici, Yüksel Temiz, Enrico Accastelli, Carlotta Guiducci, Anna Ferretti, Giulia Cappi, Elena Bianchi

The paper discusses the recent achievements in the development of chips with integrated sensing of biomolecules. In particular, it focuses on integrated sensing electrodes on silicon and presents innovative solutions for the enhanced robustness of the elec ...

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