Publications de Stanisa Raspopovic

Author Correction: Bringing sensation to prosthetic hands-chronic assessment of implanted thin-film electrodes in humans (vol 7, 51, 2023)

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

2024

Sensory-Motor Neurostimulation to Enhance Exosuit Performance

Silvestro Micera, Stanisa Raspopovic, Andrea Crema, Giacomo Valle

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...

IEEE2023

Bringing sensation to prosthetic hands-chronic assessment of implanted thin-film electrodes in humans

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses. Longevity of the electrodes is key to success, which we have improved for the polyimide-based transverse int ...

2023

Corrigendum: A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use (vol 3, 619280, 2021)

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

2022

A Software Tool for the Real-Time in Vivo Evaluation of Neural Electrodes' Selectivity

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Daniela De Luca

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

IEEE2021

A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

2021

Neurorobotics for neurorehabilitation

Stanisa Raspopovic

American Association for the Advancement of Science2021

Neural signal recording and processing in somatic neuroprosthetic applications. A review

Silvestro Micera, Stanisa Raspopovic, Andrea Cimolato

Neurointerfaces have acquired major relevance as both rehabilitative and therapeutic tools for patients with spinal cord injury, limb amputations and other neural disorders. Bidirectional neural interfaces are a key component for the functional control of ...

ELSEVIER2020

Stability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement ofin vivoperformance

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

Objective.Micro-fabricated neural interfaces based on polyimide (PI) are achieving increasing importance in translational research. The ability to produce well-defined micro-structures with properties that include chemical inertness, mechanical flexibility ...

2020

Sensitivity to temporal parameters of intraneural tactile sensory feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Background Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimulation modulate aspects of evoked se ...

BioMed Central2020

Decoding of grasping tasks from intraneural recordings in trans-radial amputee

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Objective. A major challenge in neuroprosthetics is the restoration of sensory-motor hand functions in upper-limb amputees. Neuroprostheses based on the direct re-connection of the peripheral nerves may be an interesting approach for re-establishing the na ...

2020

Brain reactions to the use of sensorized hand prosthesis in amputees

Fabrizio Vecchio, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Objective We investigated for the first time the presence of chronic changes in the functional organization of sensorimotor brain areas induced by prolonged training with a bidirectional hand prosthesis. Methods A multimodal neurophysiological and neuroima ...

2020

Cortical plasticity after hand prostheses use: Is the hypothesis of deafferented cortex "invasion" always true?

Pablo Garcia del Valle, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Objective: To study motor cortex plasticity after a period of training with a new prototype of bidirectional hand prosthesis in three left trans-radial amputees, correlating these changes with the modification of Phantom Limb Pain (PLP) in the same period. ...

ELSEVIER IRELAND LTD2020

Characterization of multi-channel intraneural stimulation in transradial amputees

Pablo Garcia del Valle, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Fiorenzo Artoni

Although peripheral nerve stimulation using intraneural electrodes has been shown to be an effective and reliable solution to restore sensory feedback after hand loss, there have been no reports on the characterization of multi-channel stimulation. A deepe ...

Springer Nature2019

Six-Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Objective Hand amputation is a highly disabling event, which significantly affects quality of life. An effective hand replacement can be achieved if the user, in addition to motor functions, is provided with the sensations that are naturally perceived whil ...

2019

Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Federica Barberi, Dario Bortolotti

Conventional leg prostheses do not convey sensory information about motion or interaction with the ground to aboveknee amputees, thereby reducing confidence and walking speed in the users that is associated with high mental and physical fatigue(1-4). The l ...

2019

Enhancing functional abilities and cognitive integration of the lower limb prosthesis

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Federica Barberi, Dario Bortolotti

Lower limb amputation (LLA) destroys the sensory communication between the brain and the external world during standing and walking. Current prostheses do not restore sensory feedback to amputees, who, relying on very limited haptic information from the st ...

2019

A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Current myoelectric prostheses allow transradial amputees to regain voluntary motor control of their artificial limb by exploiting residual muscle function in the forearm. However, the overreliance on visual cues resulting from a lack of sensory feedback i ...

AMER ASSOC ADVANCEMENT SCIENCE2019

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Stanisa Raspopovic, Marco Capogrosso, Francesco Maria Petrini, Jacopo Rigosa, Alessandra Pampaloni, Beatrice Barra

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019

Phantom somatosensory evoked potentials following selective intraneural electrical stimulation in two amputees

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

2018