Publications associées à Cascaded PID controller for anaesthesia delivery

Pencil Graphite Needle-Shaped Biosensor for Anaesthetic Monitoring in Human Serum

Sandro Carrara, Danilo Demarchi, Simone Aiassa

Direct and online continuous monitoring of anaesthetic intake by the patient's blood stream improves practices in the critical procedure of anaesthesia. Several systems have been proposed to address this challenge. Electrochemical techniques are highly app ...

IEEE2020

Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Simone Aiassa

Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to ...

IEEE2019

Live Demonstration: Quasi-Digital Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Danilo Demarchi, Francesco Grassi, Simone Aiassa

The live demonstration presents the innovative concept of a portable pen-device able to sense anaesthetic compounds over time for improved anaesthesiology practice. A custom Printed Circuit Board (PCB) manage in the event-based quasi-digital domain the sam ...

IEEE2019

IoT Bio-Electronic Multi-Panel Device for On-line Monitoring of Anaesthesia Delivery

Francesca Stradolini

After a failure of "One-Size-Fits-All" approach on traditional treatment of diseases, the age of multi-faceted personalized medicine came into being for tailoring therapy to get the best response in the highest safety margin. Personalized drug dosage is on ...

EPFL2018

Raspberry-Pi based system for propofol monitoring

Sandro Carrara, Francesca Stradolini, Abuduwaili Tuoheti, Danilo Demarchi, Tugba Kilic

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, lon ...

ELSEVIER SCIENCE BV2018

Ordering Events Based on Intentionality in Cyber-Physical Systems

Jean-Yves Le Boudec, Simon Bliudze, Maaz Mashood Mohiuddin, Wajeb Saab

We consider cyber-physical systems (CPSs) comprising a central controller that might be replicated for high-reliability, and one or more process agents. The controller receives measurements from process agents, causing it to compute and issue setpoints tha ...

2018

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employ ...

Wiley-Blackwell2017

Xenon Recovery at Room Temperature using Metal-Organic Frameworks

Daniele Ongari

Xenon is known to be a very efficient anesthetic gas, but its cost prohibits the wider use in medical industry and other potential applications. It has been shown that Xe recovery and recycling from anesthetic gas mixtures can significantly reduce its cost ...

Wiley-Blackwell2017

Towards 3D facial morphometry : facial image analysis applications in anesthesiology and 3D spectral nonrigid registration

Gabriel Louis Cuendet

In anesthesiology, the detection and anticipation of difficult tracheal intubation is crucial for patient safety. When undergoing general anesthesia, a patient who is unexpectedly difficult to intubate risks potential life-threatening complications with po ...

EPFL2017

Ordering Events Based on Intentionality in Cyber-Physical Systems

Jean-Yves Le Boudec, Simon Bliudze, Maaz Mashood Mohiuddin, Wajeb Saab

We consider cyber-physical systems (CPSs) comprising a central controller that might be replicated for high-reliability, and one or more process agents. The controller receives measurements from process agents, causing it to compute and issue setpoints tha ...

2017

WHO'S ON BOARD? Probabilistic Membership for Real-Time Distributed Control Systems

Rachid Guerraoui, David Kozhaya

To increase their dependability, distributed control systems (DCSs) need to agree in real time about crashed hosts, i.e., they need a real-time membership service. In this paper, we prove that such a service cannot be implemented deterministically if, besi ...

Ieee2016

Distributed Modifier-Adaptation Schemes for the Real-Time Optimization of Interconnected Systems in the Presence of Structural Plant-Model Mismatch

Dominique Bonvin, Predrag Milosavljevic, René Uwe Schneider

The desire to operate chemical processes in a safe and economically optimal way has motivated the development of so-called real-time optimization (RTO) methods [1]. For continuous processes, these methods aim to compute safe and optimal steady-state set ...

2016

Reliable and Real-Time Distributed Abstractions

David Kozhaya

The celebrated distributed computing approach for building systems and services using multiple machines continues to expand to new domains. Computation devices nowadays have additional sensing and communication capabilities, while becoming, at the same tim ...

EPFL2016

In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. We report on the in vivo testing of a novel noninvasively adjustable glaucoma drainage device (AGDD), which features an adjustable outflow resistance, and assess the safety and efficiency of this implant. METHODS. Under general anesthesia, the AGD ...

Association for Research in Vision and Ophthalmology2014

Effects of Isoflurane Anesthesia on Aortic Compliance and Systemic Hemodynamics in Compliant and Noncompliant Aortas

Nikolaos Stergiopoulos

Objectives: To investigate the effect of general anesthesia on aortic compliance and other cardiovascular hemodynamics in chronically instrumented pigs with compliant and noncompliant (stiff) aortas. Design: Experimental study. Setting: University animal l ...

W B Saunders Co-Elsevier Inc2013

Automatic Mallampati Classification Using Active Appearance Models

Jean-Philippe Thiran, Matteo Sorci, Gabriel Louis Cuendet, Anil Yuce

Difficult tracheal intubation assessment is an important research topic in anesthesia as failed intubations are important causes of mortality in anesthetic practice. The modified Mallampati score is widely used, alone or in conjunction with other criteria, ...

2012

Anesthesia prevents auditory perceptual learning

Alain Farron, Michael Herzog, Elisa Tartaglia, Carl Kristoffer Aberg

BACKGROUND: An auditory perceptual learning paradigm was used to investigate whether implicit memories are formed during general anesthesia. METHODS: Eighty-seven patients who had an American Society of Anesthesiologists physical status of I-III and were s ...

Lippincott, Williams & Wilkins2009

Modeling the effects of midazolam on cortical and thalamic neurons

Sean Lewis Hill

Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling ...

2009