Publications associées à Lumbar and thoracic kinematics during step-up: Comparison of three-dimensional angles between patients with chronic low back pain and asymptomatic individuals

Three-dimensional evaluation of the transverse rotator cuff muscle's resultant force angle in relation to scapulohumeral subluxation and glenoid vault morphology in nonpathological shoulders

Alexandre Terrier, Alain Farron, Matthieu Boubat, Patrick Goetti

Background: Static posterior subluxation of the humeral head (SPSH) results in glenohumeral osteoarthritis. Treatment strategies for SPSH with or without resulting osteoarthritis remain challenging. There is growing interest in evaluating the rotator cuff ...

Mosby-Elsevier2024

Targeted regeneration of spinal cord neurons across a complete injury restores walking

Marco Milano

Spinal cord injury (SCI) interrupts axonal connections between the brain and the spinal cord, and is characterized by a spectrum of sensorimotor and autonomic impairments. While spontaneous recovery is limited, recent studies have shown that functional imp ...

EPFL2023

Hypogravity modeling of upper extremities: an investigation of manual handling in the workplace

Tatiana Maillard

Experiments on the lower limbs are the only approaches being used to study how hypogravity (HG) (0 < g < 1, e.g., Moon: 1/6 g, Mars: 3/8 g) affects human movement. The goal of this study was to expand this field experimentally by investigating the effect o ...

Frontiers Media Sa2023

Unveiling the Rolling to Kayak Transition in Propelling Nanorods with Cargo Trapping and Pumping

Ignacio Pagonabarraga Mora

Magnetic nanorods driven by rotating fields in water can be rapidly steered along any direction while generating strong and localized hydrodynamic flow fields. Here we show that, when raising the frequency of the rotating field, these nanopropellers underg ...

AMER CHEMICAL SOC2023

Investigating the roles of reflexes and central pattern generators in the control and modulation of human locomotion using a physiologically plausible neuromechanical model

Auke Ijspeert, Andrea Di Russo, Stéphane Armand, Dimitar Yuriev Stanev, Anushree Bapusaheb Sabnis

Objective. Studying the neural components regulating movement in human locomotion is obstructed by the inability to perform invasive experimental recording in the human neural circuits. Neuromechanical simulations can provide insights by modeling the locom ...

Iop Publishing Ltd2023

Investigating the neuromechanical control of healthy gait modulation and pathological gaits observed in cerebral palsy using neuromuscular simulations

Andrea Di Russo

Locomotion is based on a sophisticated interaction among the environment, the musculoskeletal system, the spinal cord, and the brain locomotor areas. Quality of life is strongly related to the proper capability of this movement. However, many pathologies, ...

EPFL2023

Prefrontal engrams of long-term fear memory perpetuate pain perception

Johannes Gräff, Yechao Han

A painful episode can lead to a life-long increase in an individual's experience of pain. Fearful anticipation of imminent pain could play a role in this phenomenon, but the neurobiological underpinnings are unclear because fear can both suppress and enhan ...

NATURE PORTFOLIO2023

A Stand-Alone Augmented Reality Intervention for Chronic Pain using Embodied Systolic Stimulation

Skander Mensi, Sylvain Cardin, Oliver Alan Kannape, Robert Leeb, Fabien Bourban, Alexis Dorier, Andrea Serino

Chronic pain presents a tremendous personal, societal, and financial burden. Treatment options are often limited to managing symptoms as opposed to treating the causes, and the consequences of pharmacological treatments can be immensely harmful as evidence ...

IEEE2023

Targeted dorsal root entry zone stimulation alleviates pain due to meralgia paresthetica

Léonie Asboth, Grégoire Courtine, Nicolas Hankov, Robin Jonathan Demesmaeker, Jocelyne Bloch, Jimmy James Ravier, Molywan Vat, Viviana Aureli

Objective. Meralgia paresthetica (MP) is a mononeuropathy of the exclusively sensory lateral femoral cutaneous nerve (LFCN) that is difficult to treat with conservative treatments. Afferents from the LFCN enter the spinal cord through the dorsal root entry ...

IOP Publishing Ltd2022

Scrambler Therapy for Chronic Pain after Burns and Its Effect on the Cerebral Pain Network: A Prospective, Double-Blinded, Randomized Controlled Trial

Chang-Hyun Park

Chronic pain is common after burn injuries, and post-burn neuropathic pain is the most important complication that is difficult to treat. Scrambler therapy (ST) is a non-invasive modality that uses patient-specific electrocutaneous nerve stimulation and is ...

MDPI2022

Association of the Posterior Acromion Extension with Glenoid Retroversion: A CT Study in Normal and Osteoarthritic Shoulders

Alexandre Terrier, Alain Farron, Frédéric Vauclair, Patrick Goetti

Posterior eccentric glenoid wear is associated with higher complication rates after shoulder arthroplasty. The recently reported association between the acromion shape and glenoid retroversion in both normal and osteoarthritic shoulders remains controversi ...

MDPI2022

On the interplay effect for moving targets treated with the CyberKnife static tracking system

François Bochud, Yihan Jia

Purpose: To assess the interplay effect amplitude between different planned MU distributions and respiratory patterns in the CyberKnife system when treating moving targets with static tracking technique. Methods: Small-and Large-Respiratory Motions (SRM an ...

2021

Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates

Grégoire Courtine, Quentin Barraud, Lili Huang, Xiaomeng Zhang

Spinal cord injury (SCI) is a devastating condition characterized by loss of function, secondary to damaged spinal neurons, disrupted axonal connections, and myelin loss. Spontaneous recovery is limited, and there are no approved pharmaceutical treatments ...

2021

Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders

Robin Jonathan Demesmaeker

Neurological disorders such as spinal cord injury (SCI) massively reduce independence and quality of life. Most often, the majority of the nervous system is still fully or partially spared, but dysfunctional due to aberrant or absent descending input from ...

EPFL2021

Overcorrected Implants for Total Shoulder Arthroplasty

Yasmine Boulanaache

Glenohumeral osteoarthritis is a degenerative shoulder joint disease, which causes the breakdown of articular cartilage and bone. People affected by this disease suffer from severe pain and eventually reduced mobility and poor life quality. This disease is ...

EPFL2021

Unbiased interrogation of whole brain circuits in spinal cord injury leading to the design of a clinically relevant therapy to improve locomotion

Newton Cho

Spinal cord injury (SCI) remains a global problem, and despite decades of research there currently is no cure for this disease. Recently, significant advances in the use of neuroprosthetic rehabilitation to improve locomotor outcomes after SCI have been ma ...

EPFL2021

Propulsion module for generating wave-like motion

Auke Ijspeert, Peter Eckert

The present invention relates to a propulsion module (1) for generating wave-like motion in liquid. The propulsion module (1) comprises: a motor (7) for generating rotational motion; a set of conversion devices comprising a first conversion device (91) and ...

2020

Enhancing analgesic spinal cord stimulation for chronic pain with personalized immersive virtual reality

Robin Mange, Bruno Herbelin, Olaf Blanke, Giulio Rognini, Andrea Serino, Marco Solcà, Pavo Orepic

Spinal cord stimulation (SCS) is an approved treatment for truncal and limb neuropathic pain. However, pain relief is often suboptimal and SCS efficacy may reduce over time, requiring sometimes the addition of other pain therapies, stimulator revision, or ...

2021

The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia

Constantin Tuleasca, Anne Donnet

Introduction Gamma Knife radiosurgery (GKR) is a minimally invasive surgical option for drug-resistant essential glossopharyngeal neuralgia (GPN). The authors reviewed pain outcomes and complications in GPN patients who underwent a second or a third GKR fo ...

2020

Refinements of hybrid neurophysical volume conductor models and application to study epidural electrical stimulation of the cervical spinal cord

Nathan Antoine Greiner

After spinal cord injury (SCI), the communication between the brain and spinal neural circuits below the lesion is disrupted, leading to paralysis. Epidural electrical stimulation (EES) of the lumbosacral spinal cord has been shown to restore locomotion an ...

EPFL2020