Publications related to Environmental factor

Nanocluster aerosol formation via ozone chemistry on worn clothing: Influence of environmental parameters

Nanocluster aerosols (NCA, particles

Pergamon-Elsevier Science Ltd2024

Associations of genetic and infectious risk factors with coronary heart disease

Jacques Fellay, Flavia Aurelia Shoko Hodel, Christian Axel Wandall Thorball, Zhi Ming Xu, Roxane De La Harpe

Coronary heart disease (CHD) is one of the most pressing health problems of our time and a major cause of preventable death. CHD results from complex interactions between genetic and environmental factors. Using multiplex serological testing for persistent ...

eLIFE SCIENCES PUBL LTD2023

Out of their minds? Externalist challenges for using AI in forensic psychiatry

Marcello Ienca, Ambra D'imperio

Harnessing the power of machine learning (ML) and other Artificial Intelligence (AI) techniques promises substantial improvements across forensic psychiatry, supposedly offering more objective evaluations and predictions. However, AI-based predictions abou ...

FRONTIERS MEDIA SA2023

Predicting spatial patterns of soil bacteria under current and future environmental conditions

Nicolas Jean Philippe Guex, Jan Roelof van der Meer, Marco Pagni, Aline Buri

Soil bacteria are largely missing from future biodiversity assessments hindering comprehensive forecasts of ecosystem changes. Soil bacterial communities are expected to be more strongly driven by pH and less by other edaphic and climatic factors. Thus, al ...

2021

Human Emissions of Size-Resolved Fluorescent Aerosol Particles: Influence of Personal and Environmental Factors

Dusan Licina, Shen Yang

Human emissions of fluorescent aerosol particles (FAPs) can influence the biological burden of indoor air. Yet, quantification of FAP emissions from human beings remains limited, along with a poor understanding of the underlying emission mechanisms. To red ...

AMER CHEMICAL SOC2021

The Links between ALS and NF-κB

Bernard Schneider, Brian Donal McCabe, Emma Charlotta Källstig

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease wherein motor neu-ron degeneration leads to muscle weakness, progressive paralysis, and death within 3–5 years ofdiagnosis. Currently, the cause of ALS is unknown but, as with several neuro ...

2021

The foreign oligochaete species Quistadrilus multisetosus (Smith, 1900) in Lake Geneva: morphological and molecular characterization and environmental influences on its distribution

Benoît Jean Dominique Ferrari, Régis Lionel Vivien

The presence of the oligochaete species Quistadrilus multisetosus (Smith, 1900) originating from North America has been mentioned for several decades in Europe, the Middle East and Russia. Its distribution and abundance in Europe is still unknown but it ca ...

2020

The Indoor Chemical Human Emissions and Reactivity (ICHEAR) project: Overview of experimental methodology and preliminary results

Dusan Licina, Shen Yang

With the gradual reduction of emissions from building products, emissions from human occupants become more dominant indoors. The impact of human emissions on indoor air quality is inadequately understood. The aim of the Indoor Chemical Human Emissions and ...

WILEY2020

Global spatial analysis of toxic emissions to freshwater: operationalization for LCA

Anna Kounina Massé

PurposeThere is increasing interest in using fate and exposure models to spatially differentiate the impacts of chemical emissions. This work aims at exploring the operationalization in life cycle assessment (LCA) of spatially differentiated models for tox ...

SPRINGER HEIDELBERG2019

Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis

Jian Wang, Christian Hammer

Multiple sclerosis is an autoimmune disease that is caused by the interplay of genetic, particularly the HLA-DR15 haplotype, and environmental risk factors. How these etiologic factors contribute to generating an autoreactive CD4(+) T cell repertoire is no ...

CELL PRESS2018

Ecohydrological and Metacommunity Studies of Proliferative Kidney Disease Spread in Freshwater Salmonid Fish

Luca Carraro

Proliferative kidney disease (PKD) is a high-mortality pathology affecting freshwater salmonid populations in Europe and North America. Its causative agent, the myxozoan Tetracapsuloides bryosalmonae, has a complex life-cycle exploiting freshwater bryozoan ...

EPFL2018

Visual masking deficits in schizophrenia: A view into the genetics of the disease through an endophenotype

Michael Herzog, Jacques Fellay, Maya Roinishvili, Flavia Aurelia Shoko Hodel

Schizophrenia is a chronic disorder determined by a complex mix of genetic and environmental factors. To better understand the contributions of human genetic variation to schizophrenia, we performed a genome-wide association study of a validated endophenot ...

2018

Exploring the influence of contemporary facade design on occupant satisfaction: a preliminary study in office buildings

Marilyne Andersen, Luisa Pastore

This paper describes the preliminary findings of a post-occupancy evaluation campaign conducted on contemporary and energy-efficient office buildings with different façades treatments. The aim is to investigate occupants’ comfort and perceived productivity ...

2017

“Our Inherent Desire for Control”: a Case Study of Automation’s Impact on the Perception of Comfort

Marilyne Andersen, Thomas Bernard Paul Jusselme, Arianna Brambilla, Hamed Seiied Alavi, Himanshu Verma

To investigate the relationship between occupants’ perception of control over building elements and their comfort, we conducted a study where two prototype office rooms were compared: while the first room allowed occupants to open or close the window and c ...

ELSEVIER2017

Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro, Marino Gatto

Proliferative kidney disease (PKD) is a major threat to wild and farmed salmonid populations because of its lethal effect at high water temperatures. Its causative agent, the myxozoan Tetracapsuloides bryosalmonae, has a complex lifecycle exploiting freshw ...

National Academy of Sciences2017

Risk prediction of developing venous thrombosis in combined oral contraceptive users

Emmanuelle Logette, Valérie Buchillier

Background Venous thromboembolism (VTE) is a complex multifactorial disease influenced by genetic and environmental risk factors. An example for the latter is the regular use of combined oral contraceptives (CC), which increases the risk to develop VTE by ...

2017

Spatially explicit modeling of cholera epidemics

Flavio Finger

Understanding the epidemiology of cholera, when and where it occurs and how it spreads, is key to its prevention and control. Models can help to apprehend cholera outbreaks by providing insight into critical epidemiological processes, and may be used to ev ...

EPFL2017

Phenotypic heterogeneity driven by nutrient limitation promotes growth in fluctuating environments

Anders Meibom, Stéphane Laurent Escrig, Martin Ackermann

Most microorganisms live in environments where nutrients are limited and fluctuate over time. Cells respond to nutrient fluctuations by sensing and adapting their physiological state. Recent studies suggest phenotypic heterogeneity(1) in isogenic populatio ...

Nature Publishing Group2016

The Convergence of Systems and Reductionist Approaches in Complex Trait Analysis

Johan Auwerx, Evan Graehl Williams

Research into the genetic and environmental factors behind complex trait variation has traditionally been segregated into distinct scientific camps. The reductionist approach aims to decrypt phenotypic variability bit by bit, founded on the underlying hypo ...

2015

Cholera in the Lake Kivu region (DRC): Integrating remote sensing and spatially explicit epidemiological modeling

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Flavio Finger, Allyn Christine Knox, Marino Gatto

Mathematical models of cholera dynamics can not only help in identifying environmental drivers and processes that influence disease transmission, but may also represent valuable tools for the prediction of the epidemiological patterns in time and space as ...

American Geophysical Union2014