Publications associées à Unité motrice

Accelerometry as a tool for measuring the effects of transcranial magnetic stimulation

Pierre Theopistos Vassiliadis, Julie Duqué

Objective: We predicted that accelerometry would be a viable alternative to electromyography (EMG) for assessing fundamental Transcranial Magnetic Stimulation (TMS) measurements (e.g. Resting Motor Threshold (RMT), recruitment curves, latencies). New Metho ...

Elsevier2024

Puckered and JNK signaling in pioneer neurons coordinates the motor activity of the Drosophila embryo

Samuel William Vernon

Central nervous system organogenesis is a complex process that obeys precise architectural rules. The impact that nervous system architecture may have on its functionality remains, however, relatively unexplored. To clarify this problem, we analyze the dev ...

Nature Portfolio2023

Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Elvira Pirondini, Cyprien Alban Félicien Rivier

Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...

OXFORD UNIV PRESS2023

Motor-Unit Ordering of Blindly-Separated Surface-EMG Signals for Gesture Recognition

Pasquale Davide Schiavone, Elisa Donati

Hand gestures are one of the most natural and expressive way for humans to convey information, and thus hand gesture recognition has become a research hotspot in the human-machine interface (HMI) field. In particular, biological signals such as surface ele ...

SPRINGER INTERNATIONAL PUBLISHING AG2023

Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas

Carl Petersen, Sylvain Crochet, Romain Guiet, Vahid Esmaeili, Georgios Foustoukos, Yanqi Liu, Keita Tamura, Anastasiia Oryshchuk, Reza Asri

Excitatory and inhibitory neurons in diverse cortical regions are likely to contribute differentially to the transformation of sensory information into goal-directed motor plans. Here, we investigate the relative changes across mouse sensorimotor cortex in ...

2022

Disruption of layer-specific visual processing in a model of focal neocortical epilepsy

Silvestro Micera, Matteo Vissani

The epileptic brain is the result of a sequence of events transforming normal neuronal populations into hyperexcitable networks supporting recurrent seizure generation. These modifications are known to induce fundamental alterations of circuit function and ...

OXFORD UNIV PRESS INC2022

Breathing is coupled with voluntary initiation of mental imagery

Olaf Blanke, Oliver Alan Kannape, Hyeongdong Park

Previous research has suggested that bodily signals from internal organs are associated with diverse cortical and subcortical processes involved in sensory-motor functions, beyond homeostatic reflexes. For instance, a recent study demonstrated that the pre ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Effective connectivity in brain networks estimated using EEG signals is altered in children with ADHD

Amir Hossein Omidvarnia

This study presents a methodology developed for estimating effective connectivity in brain networks (BNs) using multichannel scalp EEG recordings. The methodology uses transfer entropy as an information transfer measure to detect pair-wise directed informa ...

PERGAMON-ELSEVIER SCIENCE LTD2021

Investigation of physiological roles of AMPK-activated protein kinase y3

Philipp Jurijvic Rhein

Clinical trials have shown that direct activators of an evolutionary-conserved metabolic sensor, AMP-activated protein kinase (AMPK), are beneficial in preventing/treating a range of metabolic disorders, including type 2 diabetes. These activators, includi ...

EPFL2021

A biomimetic electrical stimulation strategy to induce asynchronous stochastic neural activity

Silvestro Micera, Stéphanie Lacour, Edoardo D'Anna, Emanuele Formento, Sandra Gribi

Objective.Electrical stimulation is an effective method for artificially modulating the activity of the nervous system. However, current stimulation paradigms fail to reproduce the stochastic and asynchronous properties of natural neural activity. Here, we ...

2020

Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis

Estelle Emeline Raffin

Objective: We employed dual-site TMS to test whether ipsilateral functional premotor-motor connectivity is altered in relapsing-remitting Multiple Sclerosis (RR-MS) and is related to central fatigue. ...

FRONTIERS MEDIA SA2020

Cortical circuits for transforming whisker sensation into goal-directed licking

Carl Petersen, Sylvain Crochet, Vahid Esmaeili, Georgios Foustoukos, Keita Tamura, Anastasiia Oryshchuk

Animals can learn to use sensory stimuli to generate motor actions in order to obtain rewards. However, the precise neuronal circuits driving learning and execution of a specific goal-directed sensory-to-motor transformation remain to be elucidated. Here, ...

2020

Hand perceptions induced by single pulse transcranial magnetic stimulation over the primary motor cortex

Olaf Blanke, Andrea Serino, Michela Bassolino, Matteo Franza, Matteo Vissani, Giuliana Sorrentino

Background When single pulse transcranial magnetic stimulation (TMS) is applied over the primary motor cortex (M1) with sufficient intensity, it evokes muscular contractions (motor-evoked potentials, MEPs) and muscle twitches (TMS-evoked movements). Partic ...

2019

The Human-Computer Connection An Overview Of Brain-Computer Interfaces

José del Rocio Millán Ruiz

This article introduces the field of brain-computer interfaces (BCI), which allows the control of devices without the generation of any active motor output but directly from the decoding of the user's brain signals. Here we review the current state of the ...

2019

Optical cuff for optogenetic control of the peripheral nervous system

Stéphanie Lacour, Grégoire Courtine, Léonie Asboth, Frédéric Pierre Gérald Michoud, Loïc Sottas

Objective. Nerves in the peripheral nervous system (PNS) contain axons with specific motor, somatosensory and autonomic functions. Optogenetics offers an efficient approach to selectively activate axons within the nerve. However, the heterogeneous nature o ...

2018

Neural and muscular factors both contribute to plantar-flexor muscle weakness in older fallers

Jean-Baptiste Mignardot

Plantar-flexor muscles are key muscles in the control of postural sway. Older fallers present lower maximal plantar-flexor performance than older non-fallers; however, the mechanisms underlying this motor impairment remain to be elucidated. This study aime ...

PERGAMON-ELSEVIER SCIENCE LTD2018

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Roman Chrast, Nathalie Marie Géraldine Bernard

Mutations in SIGMAR1, which encodes the Sigma 1 receptor, cause a familial form of amyotrophic lateral sclerosis, but the underlying molecular mechanisms are unclear. Bernard-Marissal et al. reveal that disruption of Sigma 1 receptor function disturbs endo ...

Oxford University Press2015

Generalization of motor resonance during the observation of hand, mouth, and eye movements

Michela Bassolino

Transcranial magnetic stimulation (TMS) of the motor cortex shows that hand action observation (AO) modulates corticospinal excitability (CSE). CSE modulation alternatively maps low-level kinematic characteristics or higher-level features, like object-dire ...

Amer Physiological Soc2015

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Patrick Aebischer, Bernard Schneider, Christopher Towne, Elisabeth Anne Dirren, Julianne Bobela, Cylia Cloé Rochat

Objective: Amyotrophic lateral sclerosis is an incurable disorder mainly characterized by motoneuron degeneration. Mutations in the superoxide dismutase 1 (SOD1) gene account for 20% of familial forms of the disease. Mutant SOD1 exerts multiple pathogenic ...

Wiley-Blackwell2015

Fractal temporal organization of motricity is altered in major depression

Kamiar Aminian, Anisoara Ionescu

Objective: Motor changes in major depression (MD) may represent potential markers of treatment response. Physiological rhythms (heart rate/gait cycle/hand movements) have been recently shown to be neither random nor regular but to display a fractal tempora ...

Elsevier2012